Indican structure
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Common Name | Indican | ||
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CAS Number | 487-60-5 | Molecular Weight | 295.288 | |
Density | 1.6±0.1 g/cm3 | Boiling Point | 606.7±55.0 °C at 760 mmHg | |
Molecular Formula | C14H17NO6 | Melting Point | 57-58ºC | |
MSDS | USA | Flash Point | 320.7±31.5 °C |
Use of IndicanIndican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4[1][2]. |
Name | indican |
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Synonym | More Synonyms |
Description | Indican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4[1][2]. |
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Related Catalog | |
In Vivo | Indican ((Indoxyl-β-D-glucoside; oral; 20, 40 mg/kg; single dose) increases the systemic exposure and MRT of MTX through inhibition on multiple anion transporters including OAT 1, OAT 3 and MRP 4 by the major metabolite IS[1]. Animal Model: Male Spraguee Dawley rats weighing 330-400 g[1] Dosage: 20, 40 mg/kg Administration: Orally Result: Increased the systemic exposure and multidrug resistance-associated protein (MRP) of Methotrexate (MTX; 5.0 mg/kg). |
References |
Density | 1.6±0.1 g/cm3 |
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Boiling Point | 606.7±55.0 °C at 760 mmHg |
Melting Point | 57-58ºC |
Molecular Formula | C14H17NO6 |
Molecular Weight | 295.288 |
Flash Point | 320.7±31.5 °C |
Exact Mass | 295.105591 |
PSA | 115.17000 |
LogP | -0.75 |
Vapour Pressure | 0.0±1.8 mmHg at 25°C |
Index of Refraction | 1.715 |
Storage condition | −20°C |
Water Solubility | H2O: 0.1 M at 20 °C, clear to slightly hazy, colorless to faint yellow-green |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Safety Phrases | S22-S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2934999090 |
Precursor 0 | |
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DownStream 1 | |
HS Code | 2934999090 |
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Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
A modified m-CP medium for enumerating Clostridium perfringens from water samples.
Can. J. Microbiol. 34 , 78, (1988) Medium m-CP, designed for the isolation of Clostridium perfringens from water samples, contains indoxyl beta-D-glucoside, an expensive chemical that is present at a high concentration in this medium. ... |
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[Determination of indican in Polygonum tinctorium ait. in various growth periods].
Zhong Yao Tong Bao 13(11) , 11-3, 61-2, (1988)
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Distribution, diversity, and seasonality of waterborne salmonellae in a rural watershed.
Appl. Environ. Microbiol. 75(5) , 1248-55, (2009) Salmonella outbreaks from contaminated water and nonanimal foods (e.g., produce) are increasingly reported. To address the environment as a potential source of pathogenic Salmonella, we investigated l... |
Indikan |
Plant indican |
Indican |
Indole, 3- (β-D-glucopyranosyloxy)- |
3-Indolyl-b-D-glucopyranoside |
3-Indole-D-glucoside Hydrate |
Indoxyl-D-glucoside Hydrate |
Indoxyl β-D-glucoside |
1H-Indol-3-yl β-D-glucopyranoside |
1H-Indol-3-yl β-glucopyranoside |
Indoxyl-b-D-glucoside |
3-Indolyl-D-glucoside Hydrate |
Indoxyl-β-D-glucoside |
Indican Hydrate |
Uroxanthin |
3-Indoxyl-beta-D-glucopyranoside |
3-Indoxyl-D-glucoside Hydrate |
3-(b-Glucosido)indole |
1H-Indol-3-yl-b-D-glucopyranoside |
MFCD00047169 |
Indole, 3-(β-D-glucopyranosyloxy)- |
3-Indoxyl-β-D-glucopyranoside |
β-D-Glucopyranoside, 1H-indol-3-yl |