Niranthin

Modify Date: 2024-01-11 19:36:19

Niranthin structure	Common Name	Niranthin
	CAS Number	50656-77-4	Molecular Weight	432.507
	Density	1.1±0.1 g/cm3	Boiling Point	559.5±50.0 °C at 760 mmHg
	Molecular Formula	C₂₄H₃₂O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	221.8±30.0 °C

Use of Niranthin

Niranthin, a lignan with a wide spectrum of pharmacological activities. Niranthin is a potent and non-competitive inhibitor of heterodimeric type IB topoisomerase of L. donovani. Niranthin can be used for the research of drug-resistant leishmaniasis treatment[1].

Name	Niranthin
Synonym	More Synonyms

Description	Niranthin, a lignan with a wide spectrum of pharmacological activities. Niranthin is a potent and non-competitive inhibitor of heterodimeric type IB topoisomerase of L. donovani. Niranthin can be used for the research of drug-resistant leishmaniasis treatment[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase Research Areas >> Infection Research Areas >> Inflammation/Immunology
Target	Topoisomerase
References	[1]. Sayan Chowdhury, et al. The lignan niranthin poisons Leishmania donovani topoisomerase IB and favours a Th1 immune response in mice. EMBO Mol Med. 2012 Oct;4(10):1126-43.

Density	1.1±0.1 g/cm3
Boiling Point	559.5±50.0 °C at 760 mmHg
Molecular Formula	C₂₄H₃₂O₇
Molecular Weight	432.507
Flash Point	221.8±30.0 °C
Exact Mass	432.214813
PSA	64.61000
LogP	4.40
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.534