Minecoside

Modify Date: 2024-01-10 06:51:37

Minecoside structure	Common Name	Minecoside
	CAS Number	51005-44-8	Molecular Weight	538.50
	Density	1.6±0.1 g/cm3	Boiling Point	815.9±65.0 °C at 760 mmHg
	Molecular Formula	C₂₅H₃₀O₁₃	Melting Point	142℃
	MSDS	Chinese USA	Flash Point	275.7±27.8 °C
	Symbol	GHS07	Signal Word	Warning

Common Name	Minecoside
CAS Number	51005-44-8	Molecular Weight	538.50
Density	1.6±0.1 g/cm3	Boiling Point	815.9±65.0 °C at 760 mmHg
Molecular Formula	C₂₅H₃₀O₁₃	Melting Point	142℃
MSDS	Chinese USA	Flash Point	275.7±27.8 °C
Symbol	GHS07	Signal Word	Warning

Purity		Quantity		Budget		Inquiry

Use of Minecoside

Minecoside is a CXCR4/STAT3 inhibitor with anticancer and anti-inflammatory activity. Minecoside decreases CXCR4 expression and suppresses STAT3 activation, thus to inhibit CXCL 12-induced invasion. Minecoside potently inhibits cancer metastasis and promotes apoptotic progression[1][2].

Name	(1aS,1bS,2S,5aR,6S,6aS)-2-(β-D-Glucopyranosyloxy)-1a-(hydroxymeth yl)-1a,1b,2,5a,6,6a-hexahydrooxireno[4,5]cyclopenta[1,2-c]pyran-6 -yl (2E)-3-(3-hydroxy-4-methoxyphenyl)acrylate
Synonym	More Synonyms

Description	Minecoside is a CXCR4/STAT3 inhibitor with anticancer and anti-inflammatory activity. Minecoside decreases CXCR4 expression and suppresses STAT3 activation, thus to inhibit CXCL 12-induced invasion. Minecoside potently inhibits cancer metastasis and promotes apoptotic progression[1][2].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> STAT Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> STAT Signaling Pathways >> GPCR/G Protein >> CXCR Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> CXCR
Target	CXCR4; STAT3
References	[1]. Kim B, et al. Minecoside Modulates Cell Invasion via Regulation of CXCR4 Expression in Breast and Colon Cancer Cells. Planta Med. 2020 Mar;86(5):331-337. [2]. Kim B, et al. Minecoside promotes apoptotic progression through STAT3 inactivation in breast cancer cells. Oncol Lett. 2022 Mar;23(3):94.

Density	1.6±0.1 g/cm3
Boiling Point	815.9±65.0 °C at 760 mmHg
Melting Point	142℃
Molecular Formula	C₂₅H₃₀O₁₃
Molecular Weight	538.50
Flash Point	275.7±27.8 °C
Exact Mass	538.168640
PSA	197.13000
LogP	-2.66
Vapour Pressure	0.0±3.1 mmHg at 25°C
Index of Refraction	1.678
Storage condition	?20°C

Minecoside MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319
Precautionary Statements	P305 + P351 + P338
Hazard Codes	Xi
Risk Phrases	36
Safety Phrases	26
RIDADR	NONH for all modes of transport

(1aS,1bS,2S,5aR,6S,6aS)-2-(β-D-Glucopyranosyloxy)-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[4,5]cyclopenta[1,2-c]pyran-6-yl (2E)-3-(3-hydroxy-4-methoxyphenyl)acrylate

2-Propenoic acid, 3-(3-hydroxy-4-methoxyphenyl)-, (1aS,1bS,2S,5aR,6S,6aS)-2-(β-D-glucopyranosyloxy)-1a,1b,2,5a,6,6a-hexahydro-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-6-yl ester, (2E)-