substance P (3-11)

Modify Date: 2024-01-02 06:29:29

substance P (3-11) structure	Common Name	substance P (3-11)
	CAS Number	51165-11-8	Molecular Weight	1094.329
	Density	1.3±0.1 g/cm3	Boiling Point	1537.9±65.0 °C at 760 mmHg
	Molecular Formula	C₅₂H₇₉N₁₃O₁₁S	Melting Point	N/A
	MSDS	N/A	Flash Point	883.9±34.3 °C

Use of substance P (3-11)

Substance P (3-11) is a substance P (SP) fragment peptide that can cross the BBB. Substance P (3-11) has contracting activities on guinea pig ileum. Substance P (3-11) also promotes human monocyte chemotaxis [1][2][5].

Name	L-Methionyl-L-leucylglycyl-L-phenylalanyl-L-phenylalanyl-L-glutaminyl-L-glutaminyl-L-prolyl-L-lysinamide
Synonym	More Synonyms

Description	Substance P (3-11) is a substance P (SP) fragment peptide that can cross the BBB. Substance P (3-11) has contracting activities on guinea pig ileum. Substance P (3-11) also promotes human monocyte chemotaxis [1][2][5].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vitro	Substance P (3-11) 可渗透 BBMEC 单层，渗透速率为 1.92 x 105 cm/s[2] Substance P (3-11) 在改进的 Boyden 室试验中促进人单核细胞趋化性[3]
In Vivo	Substance P (3-11) (30 nmol/kg，静脉输注) 增加大鼠血浆中组胺水平[4]
References	[1]. Yanaihara N, et al. Immunological aspects of secretin, substance P, and VIP. Gastroenterology. 1977 Apr;72(4 Pt.2):803-10. [2]. Chappa AK, et al. Characteristics of substance P transport across the blood-brain barrier. Pharm Res. 2006 Jun;23(6):1201-8. [3]. Ruff MR, et al. Substance P receptor-mediated chemotaxis of human monocytes. Peptides. 1985;6 Suppl 2:107-11. [4]. Sertl K, et al. Substance P: the relationship between receptor distribution in rat lung and the capacity of substance P to stimulate vascular permeability. Am Rev Respir Dis. 1988 Jul;138(1):151-9. [5]. Freed AL, et al. Investigation of substance P transport across the blood-brain barrier. Peptides. 2002 Jan;23(1):157-65.

Density	1.3±0.1 g/cm3
Boiling Point	1537.9±65.0 °C at 760 mmHg
Molecular Formula	C₅₂H₇₉N₁₃O₁₁S
Molecular Weight	1094.329
Flash Point	883.9±34.3 °C
Exact Mass	1093.574219
LogP	0.65
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.583

L-Lysinamide, L-methionyl-L-leucylglycyl-L-phenylalanyl-L-phenylalanyl-L-glutaminyl-L-glutaminyl-L-prolyl-

L-Methionyl-L-leucylglycyl-L-phenylalanyl-L-phenylalanyl-L-glutaminyl-L-glutaminyl-L-prolyl-L-lysinamide

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: substance P (3-11)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Taiwan Oyi peptide Co. Ltd
China
Product Name: substance P (3-11)
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Delivery: 1 Day
Contact: Vinnie
Email: Jamie@api-made.com

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