Clanfenur

Modify Date: 2024-01-14 17:07:09

Clanfenur Structure
Clanfenur structure
Common Name Clanfenur
CAS Number 51213-99-1 Molecular Weight 335.76
Density 1.371g/cm3 Boiling Point N/A
Molecular Formula C16H15ClFN3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Clanfenur


Clanfenur is a substituted benzoylphenylurea, an analogue of the pesticide fenfluramide, with potential antineoplastic activity. Clanfenur can bind to the colchicine-binding site on β-tubulin, inhibit microtubule polymerization, and thus prevent tumor cell replication[1].

 Names

Name Clanfenur
Synonym More Synonyms

 Clanfenur Biological Activity

Description Clanfenur is a substituted benzoylphenylurea, an analogue of the pesticide fenfluramide, with potential antineoplastic activity. Clanfenur can bind to the colchicine-binding site on β-tubulin, inhibit microtubule polymerization, and thus prevent tumor cell replication[1].
Related Catalog
References

[1]. J D Jonkman-de Vries, et al. Pharmaceutical development of a parenteral formulation of the investigational anticancer drug clanfenur. PDA J Pharm Sci Technol. 1997 Mar-Apr;51(2):89-95.   

 Chemical & Physical Properties

Density 1.371g/cm3
Molecular Formula C16H15ClFN3O2
Molecular Weight 335.76
Exact Mass 335.08400
PSA 61.44000
LogP 3.97090
Index of Refraction 1.64
Storage condition -20℃

 Safety Information

HS Code 2924299090

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

1-(2-Dimethylaminoethyl)-piperazine
dimethyl(2-piperazinylethyl)amine
1-(2-N,N-dimethylamino-6-fluorobenzoyl)-3-(4-chlorophenyl)urea
N,N-Dimethyl-2-(piperazin-1-yl)ethanamine
N-(CH2)2NMe2-piperazine
4-(2-dimethylaminoethyl)piperazine
dimethyl(2-piperazin-1-yl-ethyl)amine
N-[[(4-chlorophenyl)amino]carbonyl]-2-(dimethylamino)-6-fluorobenzamide
1-(2-N,N-dimethyl)-ethylpiperazine
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