o-Phenanthroline monohydrate

Modify Date: 2024-01-02 13:10:46

o-Phenanthroline monohydrate Structure
o-Phenanthroline monohydrate structure
Common Name o-Phenanthroline monohydrate
CAS Number 5144-89-8 Molecular Weight 198.221
Density 1.10 Boiling Point 365.1ºC at 760 mmHg
Molecular Formula C12H10N2O Melting Point 100-104 °C(lit.)
MSDS Chinese USA Flash Point 164.8ºC
Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger

 Use of o-Phenanthroline monohydrate


o-Phenanthroline monohydrate (1,10-Phenanthroline monohydrate), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline monohydrate forms a red chelate with Fe2+ that absorbs maximally at 510 nm[1].

 Names

Name 1,10-Phenanthroline hydrate
Synonym More Synonyms

 o-Phenanthroline monohydrate Biological Activity

Description o-Phenanthroline monohydrate (1,10-Phenanthroline monohydrate), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline monohydrate forms a red chelate with Fe2+ that absorbs maximally at 510 nm[1].
Related Catalog
References

[1]. Guan NanMu, et al. Synergistic inhibition between o-phenanthroline and chloride ion on cold rolled steel corrosion in phosphoric acid. Materials Chemistry and Physics Volume 86, Issue 1, 15 July 2004, Pages 59-68.

 Chemical & Physical Properties

Density 1.10
Boiling Point 365.1ºC at 760 mmHg
Melting Point 100-104 °C(lit.)
Molecular Formula C12H10N2O
Molecular Weight 198.221
Flash Point 164.8ºC
Exact Mass 198.079315
PSA 35.01000
LogP 2.71870
Storage condition Store at RT.
Stability Stable. Incompatible with iron, other heavy metals, strong oxidizing agents, strong acids.
Water Solubility <0.01 g/100 mL at 21 ºC

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SF8437000
CHEMICAL NAME :
1,10-Phenanthroline, monohydrate
CAS REGISTRY NUMBER :
5144-89-8
LAST UPDATED :
199504
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C12-H8-N2.H2-O
MOLECULAR WEIGHT :
198.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Rodent - mouse Ascites tumor
DOSE/DURATION :
5 umol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,4092,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7001 No. of Facilities: 63 (estimated) No. of Industries: 6 No. of Occupations: 4 No. of Employees: 364 (estimated) No. of Female Employees: 27 (estimated)

 Safety Information

Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger
Hazard Statements H301-H410
Precautionary Statements P273-P301 + P310-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T:Toxic
Risk Phrases R25;R50/53
Safety Phrases S45-S60-S61
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS SF8437000
Packaging Group III
Hazard Class 6.1
HS Code 29339990

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

1,10-Phenanthroline hydrate (1:1)
1,10-PHENANTHROLINE H2O
1,10-Phenanthroline hydrate
1,10-phehanthroline monohydrate
EINECS 200-629-2
1,10-phenanthroline monohydrate
4,5-Phenanthrolinemonohydrate
O-PHENANTHROLINE MONOHYDRATE
ORTHO-PHENANTHROLINE
1,10-phenanthroline-hydrate
MFCD00149973
1,10'-phenahthroline monohydrate
1,10-Phenanthroline, hydrate (1:1)
1,10-PHENANTHROLINE AR
O-PHENANTHROLINE HYDRATE
1,10-phenanthrolinemonorate
1,10-PHENANTHROLINE AR (H2O)
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