Karanjin

Modify Date: 2024-01-02 17:16:38

Karanjin Structure
Karanjin structure
 Common Name Karanjin
CAS Number 521-88-0 Molecular Weight 292.285
Density 1.4±0.1 g/cm3 Boiling Point 463.0±45.0 °C at 760 mmHg
Molecular Formula C18H12O4 Melting Point 156ºC
MSDS N/A Flash Point 233.8±28.7 °C

 Use of Karanjin


Karanjin is a major active furanoflavonol constituent of Fordia cauliflora. Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arrest and enhance apoptosis[1][2].

 Names

Name 3-Methoxy-2-phenyl-4H-furo[2,3-h]chromen-4-one
Synonym More Synonyms

 Karanjin Biological Activity

Description Karanjin is a major active furanoflavonol constituent of Fordia cauliflora. Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arrest and enhance apoptosis[1][2].
Related Catalog
References

[1]. Jaiswal N, et al.Karanjin from Pongamia pinnata induces GLUT4 translocation in skeletal muscle cells in a phosphatidylinositol-3-kinase-independent manner. Eur J Pharmacol. 2011 Nov 16;670(1):22-8.

[2]. Guo JR, et al. Effects of karanjin on cell cycle arrest and apoptosis in human A549, HepG2 and HL-60 cancercells. Biol Res. 2015 Jul 26;48:40.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 463.0±45.0 °C at 760 mmHg
Melting Point 156ºC
Molecular Formula C18H12O4
Molecular Weight 292.285
Flash Point 233.8±28.7 °C
Exact Mass 292.073547
PSA 52.58000
LogP 3.29
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.678

 Safety Information

Safety Phrases S22-S24/25
RTECS DX1500000
HS Code 2932999099

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Karanjin
4H-Furo[2,3-h]-1-benzopyran-4-one, 3-methoxy-2-phenyl-
3-Methoxy-2-phenyl-4H-furo[2,3-h]-1-benzopyran-4-one
3-Methoxy-2-phenyl-4H-furo[2,3-h]chromen-4-one
3-methoxy-2-phenylfuro[2,3-h]chromen-4-one
MFCD01740600
3-Methoxy-2-phenyl-4H-furo(2,3-h)(1)benzopyran-4-one
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