521-88-0

521-88-0 structure

Name: Karanjin
Chemical Name: 3-Methoxy-2-phenyl-4H-furo[2,3-h]chromen-4-one
CAS Number: 521-88-0
Molecular Formula: C₁₈H₁₂O₄
Molecular Weight: 292.285
Catalog: Biochemical Peptide
Create Date: 2018-07-09 15:39:20
Modify Date: 2024-01-02 17:16:38
Karanjin is a major active furanoflavonol constituent of Fordia cauliflora. Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arrest and enhance apoptosis[1][2].

Name	3-Methoxy-2-phenyl-4H-furo[2,3-h]chromen-4-one
Synonyms	Karanjin 4H-Furo[2,3-h]-1-benzopyran-4-one, 3-methoxy-2-phenyl- 3-Methoxy-2-phenyl-4H-furo[2,3-h]-1-benzopyran-4-one 3-Methoxy-2-phenyl-4H-furo[2,3-h]chromen-4-one 3-methoxy-2-phenylfuro[2,3-h]chromen-4-one MFCD01740600 3-Methoxy-2-phenyl-4H-furo(2,3-h)(1)benzopyran-4-one

Description	Karanjin is a major active furanoflavonol constituent of Fordia cauliflora. Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arrest and enhance apoptosis[1][2].
Related Catalog	Signaling Pathways >> Epigenetics >> AMPK Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> AMPK
References	[1]. Jaiswal N, et al.Karanjin from Pongamia pinnata induces GLUT4 translocation in skeletal muscle cells in a phosphatidylinositol-3-kinase-independent manner. Eur J Pharmacol. 2011 Nov 16;670(1):22-8. [2]. Guo JR, et al. Effects of karanjin on cell cycle arrest and apoptosis in human A549, HepG2 and HL-60 cancercells. Biol Res. 2015 Jul 26;48:40.

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%