Lexithromycin

Modify Date: 2024-01-10 17:33:40

Lexithromycin Structure
Lexithromycin structure
Common Name Lexithromycin
CAS Number 53066-26-5 Molecular Weight 762.96800
Density 1.26g/cm3 Boiling Point 824.6ºC at 760mmHg
Molecular Formula C38H70N2O13 Melting Point N/A
MSDS N/A Flash Point 452.5ºC

 Use of Lexithromycin


Lexithromycin is an erythromycin A derivative, with antibacterial activity.

 Names

Name (E)-9-deoxo-9-methoxyiminoerythromycin A
Synonym More Synonyms

 Lexithromycin Biological Activity

Description Lexithromycin is an erythromycin A derivative, with antibacterial activity.
Related Catalog
Target

Bacterial[1]

In Vitro Lexithromycin is an erythromycin A derivative, with antibacterial activity. Lexithromycin shows minimal inhibitory concentration (MIC) of 0.06 μg/mL against S. pyogenes CN10A and Streptococcus sp. 64/848C, 0.25 μg/mL against Staphylococcus aureus Oxford, 0.5 μg/mL against S. aureus Russell and S. aureus T2, 4 μg/mL against S. pyogenes CN10A and Haemophilus influenzae Wy 21[1].
References

[1]. Hunt E, et al. Erythromycin A 11,12-methylene acetal. J Antibiot (Tokyo). 1988 Nov;41(11):1644-8.

 Chemical & Physical Properties

Density 1.26g/cm3
Boiling Point 824.6ºC at 760mmHg
Molecular Formula C38H70N2O13
Molecular Weight 762.96800
Flash Point 452.5ºC
Exact Mass 762.48800
PSA 198.43000
LogP 2.21890
Index of Refraction 1.543
Storage condition 2-8℃

 Synthetic Route

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Lexithromycin Structure

Lexithromycin

CAS#:53066-26-5

Literature: Everett, Jeremy R.; Hatton, Ian K.; Hunt, Eric; Tyler, John W.; Williams, David J. Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1989 , p. 1719 - 1728

 Synonyms

(E)-9-chloro-4-methyl-8-(tetrahydro-2H-pyran-2-yloxy)-4-nonenoic acid
4-Nonenoic acid,9-chloro-4-methyl-8-[(tetrahydro-2H-pyran-2-yl)oxy]