Chiniofon

Modify Date: 2024-01-08 21:18:45

Chiniofon Structure
Chiniofon structure
Common Name Chiniofon
CAS Number 547-91-1 Molecular Weight 351.12
Density 2.2±0.1 g/cm3 Boiling Point N/A
Molecular Formula C9H6INO4S Melting Point 269-270 °C (dec.)(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS05
GHS05
Signal Word Danger

 Use of Chiniofon


Ferron (8-Hydroxy-7-iodo-5-quinolinesulfonic acid) has antiseptic and antifungal activity. Ferron can prevent skin and mucosa bacterial irritations and inflammations[1].

 Names

Name Chiniofon
Synonym More Synonyms

 Chiniofon Biological Activity

Description Ferron (8-Hydroxy-7-iodo-5-quinolinesulfonic acid) has antiseptic and antifungal activity. Ferron can prevent skin and mucosa bacterial irritations and inflammations[1].
Related Catalog
References

[1]. Pippi B, et al. New insights into the mechanism of antifungal action of 8-hydroxyquinolines. Saudi Pharm J. 2019 Jan;27(1):41-48.  

 Chemical & Physical Properties

Density 2.2±0.1 g/cm3
Melting Point 269-270 °C (dec.)(lit.)
Molecular Formula C9H6INO4S
Molecular Weight 351.12
Exact Mass 350.906219
PSA 95.87000
LogP 0.38
Index of Refraction 1.776
Stability Stable.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VC2800000
CHEMICAL NAME :
5-Quinolinesulfonic acid, 8-hydroxy-7-iodo-
CAS REGISTRY NUMBER :
547-91-1
BEILSTEIN REFERENCE NO. :
0223832
LAST UPDATED :
199706
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C9-H6-I-N-O4-S
MOLECULAR WEIGHT :
351.12
WISWESSER LINE NOTATION :
T66 BNJ GSWQ II JQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 3,44,1948
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 63,122,1938
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 63,122,1938
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 43,495,1954

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes C: Corrosive;
Risk Phrases R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 2585 8/PG 3
WGK Germany 2
RTECS VC2800000
Packaging Group III
Hazard Class 8.0
HS Code 2933499090

 Synthetic Route

~%

Chiniofon Structure

Chiniofon

CAS#:547-91-1

Literature: Chim. farm. Promysl., , p. 109 Chem. Zentralbl., , vol. 106, # II p. 3105

 Customs

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles11

More Articles
Hydroxyl radicals cause fluctuation in intracellular ferrous ion levels upon light exposure during photoreceptor cell death.

Exp. Eye Res. 129 , 24-30, (2014)

Iron accumulation is a potential pathogenic event often seen in age-related macular degeneration (AMD) patients. In this study, we focused on the relationship between AMD pathology and concentrations ...

Proton-transfer compounds of 8-hydroxy-7-iodoquinoline-5-sulfonic acid (ferron) with 4-chloroaniline and 4-bromoaniline.

Acta Crystallogr. C 63(Pt 7) , o405-7, (2007)

The crystal structures of the proton-transfer compounds of ferron (8-hydroxy-7-iodoquinoline-5-sulfonic acid) with 4-chloroaniline and 4-bromoaniline, namely 4-chloroanilinium 8-hydroxy-7-iodoquinolin...

Polyaluminum chloride with high Al30 content as removal agent for arsenic-contaminated well water.

Water Res. 46(1) , 53-62, (2012)

Polyaluminum chloride (PACl) is a well-established coagulant in water treatment with high removal efficiency for arsenic. A high content of Al(30) nanoclusters in PACl improves the removal efficiency ...

 Synonyms

7-iodo-8-hydroxyquinoline-5-sulphonic acid
7-iodo-8-hydroxyquinoline-5-sulfonic acid
Chinoiodine
quiniophen
Chinoiodin
UNII-6E8Y02XFEI
meditrene
EINECS 208-938-4
8-hydroxy-7-iodoquinoline-5-sulfonic acid
ferron
CHINIOFON ACID
5-Quinolinesulfonic acid, 8-hydroxy-7-iodo-
LORETIN
m-Iodo-o-hydroxyquinolineanasulfonic Acid
MFCD00006793
7-Iodo-8-hydroxyquinolinium 5-sulfonate
8-hydroxy-7-iodoquinolinium-5-sulphonate
8-Hydroxy-7-iodo-5-quinolinesulfonic acid
Chiniofon
yellon
8-hydroxy-7-iodoquinoline-5-sulphonic acid
Quiniofon
7-Iodo-8-Hydroxychinolin 5-Sulphonic Acid