(15S,16E)-16,17,20,21-Tetradehydro-16-formyl-18,19-secoyohimban-19-oic acid methyl ester

Modify Date: 2024-02-08 19:00:35

(15S,16E)-16,17,20,21-Tetradehydro-16-formyl-18,19-secoyohimban-19-oic acid methyl ester structure	Common Name	(15S,16E)-16,17,20,21-Tetradehydro-16-formyl-18,19-secoyohimban-19-oic acid methyl ester
	CAS Number	5523-37-5	Molecular Weight	350.41
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₂N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (15S,16E)-16,17,20,21-Tetradehydro-16-formyl-18,19-secoyohimban-19-oic acid methyl ester

Vallesiachotamine, a known monoterpene indole alkaloid, possesses anti-tumor activity[1].

Name	methyl (2S)-2-[(E)-1-oxobut-2-en-2-yl]-1,2,6,7,12,12b-hexahydroindolo[2,3-a]quinolizine-3-carboxylate
Synonym	More Synonyms

Description	Vallesiachotamine, a known monoterpene indole alkaloid, possesses anti-tumor activity[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
In Vitro	Vallesiachotamine induces G0/G1 arrest and increased the proportion of sub-G1 hypodiploid cells (at 11 μM and 22 μM) and this effect is not dependent on time of incubation. Vallesiachotamine acts by promoting G0/G1 cell cycle arrest, apoptosis and necrosis[1].
References	[1]. Paula R O Soares, et al. In vitro antiproliferative effects of the indole alkaloid vallesiachotamine on human melanoma cells. Paula R O Soares. 2012 Mar;35(3):565-71.

Molecular Formula	C₂₁H₂₂N₂O₃
Molecular Weight	350.41
Exact Mass	350.16300
PSA	62.40000
LogP	3.22700

18,19-Secoyohimban-19-oic acid,16,17,20,21-tetradehydro-16-formyl-,methyl ester,(15beta,16E)