Nepetoidin B

Modify Date: 2024-01-02 08:03:52

Nepetoidin B Structure
Nepetoidin B structure
Common Name Nepetoidin B
CAS Number 55486-06-1 Molecular Weight 314.29
Density 1.5±0.1 g/cm3 Boiling Point 587.4±50.0 °C at 760 mmHg
Molecular Formula C17H14O6 Melting Point N/A
MSDS N/A Flash Point 219.4±23.6 °C

 Use of Nepetoidin B


Nepetoidin B, an anti-inflammatory agent, inhibits inflammation by modulating the NF-κB and Nrf2/HO-1 signaling pathways. Nepetoidin B also has antifungal and antibacterial activity. Nepetoidin B is a natural product that can be obtained from Salvia plebeia R. Br. Nepetoidin B can be used in anti-inflammatory and anti-infectious research[1][2].

 Names

Name Nepetoidin B
Synonym More Synonyms

 Nepetoidin B Biological Activity

Description Nepetoidin B, an anti-inflammatory agent, inhibits inflammation by modulating the NF-κB and Nrf2/HO-1 signaling pathways. Nepetoidin B also has antifungal and antibacterial activity. Nepetoidin B is a natural product that can be obtained from Salvia plebeia R. Br. Nepetoidin B can be used in anti-inflammatory and anti-infectious research[1][2].
Related Catalog
Target

NF-κB, bacterial, fungal[1][2].

References

[1]. Kim M, et al. Nepetoidin B from Salvia plebeia R. Br. Inhibits Inflammation by Modulating the NF-κB and Nrf2/HO-1 Signaling Pathways in Macrophage Cells. Antioxidants (Basel). 2021 Jul 28;10(8):1208.  

[2]. Wu X, et al. Nepetoidin B, a Natural Product, Inhibits LPS-stimulated Nitric Oxide Production via Modulation of iNOS Mediated by NF-κB/MKP-5 Pathways. Phytother Res. 2017 Jul;31(7):1072-1077.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 587.4±50.0 °C at 760 mmHg
Molecular Formula C17H14O6
Molecular Weight 314.29
Flash Point 219.4±23.6 °C
Exact Mass 314.079041
LogP 2.67
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.752
Storage condition 2-8℃

 Safety Information

Hazard Codes Xi

 Synonyms

(Z)-2-(3,4-Dihydroxyphenyl)vinyl (2E)-3-(3,4-dihydroxyphenyl)acrylate
2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, (Z)-2-(3,4-dihydroxyphenyl)ethenyl ester, (2E)-
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