Ophiobolin B

Modify Date: 2024-01-12 12:46:07

Ophiobolin B Structure
Ophiobolin B structure
 Common Name Ophiobolin B
CAS Number 5601-74-1 Molecular Weight 402.56700
Density N/A Boiling Point N/A
Molecular Formula C25H38O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ophiobolin B


Ophiobolin B, a sesterterpene metabolite of Helminthosporium oryzae, inhibits proton extrusion from maize coleoptiles. Ophiobolin B inhibits fusicoccin (FC) promoted proton extrusion, potassium uptake and cell enlargement[1]. The MIC values with the antifungal effect of Ophiobolins B on different zygomycetes is 25–50 μg/mL[2].

 Names

Name Ophiobolin B
Synonym More Synonyms

 Ophiobolin B Biological Activity

Description Ophiobolin B, a sesterterpene metabolite of Helminthosporium oryzae, inhibits proton extrusion from maize coleoptiles. Ophiobolin B inhibits fusicoccin (FC) promoted proton extrusion, potassium uptake and cell enlargement[1]. The MIC values with the antifungal effect of Ophiobolins B on different zygomycetes is 25–50 μg/mL[2].
Related Catalog
Target

Fungal[2]

References

[1]. Gianani L, et al. Effects of ophiobolin B on cell enlargement and H(+)/K (+) exchange in maize coleoptile tissues. Planta. 1979 Jan;146(3):271-4.

[2]. Krizsán K, et al. Effect of the sesterterpene-type metabolites, ophiobolins A and B, on zygomycetes fungi. FEMS Microbiol Lett. 2010 Dec;313(2):135-40.

 Chemical & Physical Properties

Molecular Formula C25H38O4
Molecular Weight 402.56700
Exact Mass 402.27700
PSA 74.60000
LogP 4.39160

 Synonyms

3,14-Dihydroxy-5-oxoophiobola-7,19-dien-25-al
Cochliobolin B
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