Sclareolide

Modify Date: 2024-01-02 09:04:14

Sclareolide Structure
Sclareolide structure
Common Name Sclareolide
CAS Number 564-20-5 Molecular Weight 250.376
Density 1.0±0.1 g/cm3 Boiling Point 321.4±10.0 °C at 760 mmHg
Molecular Formula C16H26O2 Melting Point 124-126ºC
MSDS Chinese USA Flash Point 132.4±16.4 °C

 Use of Sclareolide


Sclareolide is isolated from the flower of Salvia sclarea with antibacterial and cytotoxic activities[1].

 Names

Name (3aR)-(+)-Sclareolide
Synonym More Synonyms

 Sclareolide Biological Activity

Description Sclareolide is isolated from the flower of Salvia sclarea with antibacterial and cytotoxic activities[1].
Related Catalog
Target

IC50: bacterial[1]

In Vitro Sclareolide has a good antibacterial activity against Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27950, Escherichia coli ATCC 25922 and Enterococcus faecalis ATCC 29212[1].
References

[1]. Hayet E, et al. Antibacterial and cytotoxic activity of the acetone extract of the flowers of Salvia sclarea and some natural products.Pak J Pharm Sci. 2007 Apr;20(2):146-8.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 321.4±10.0 °C at 760 mmHg
Melting Point 124-126ºC
Molecular Formula C16H26O2
Molecular Weight 250.376
Flash Point 132.4±16.4 °C
Exact Mass 250.193283
PSA 26.30000
LogP 4.32
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.490

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases 24/25
RIDADR NONH for all modes of transport
WGK Germany 2

 Synthetic Route

 Synonyms

(3aR,9aS,9bR)-3a,6,6,9a-Tetramethyldecahydronaphtho[2,1-b]furan-2(1H)-one
Naphtho[2,1-b]furan-2(1H)-one, decahydro-3a,6,6,9a-tetramethyl-, (3aR,9aS,9bR)-
(3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyl-1,4,5,5a,7,8,9,9b-octahydrobenzo[e][1]benzofuran-2-one
Sclareolide
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