6-Methoxy-9-(2-C-Methyl-beta-D-ribofuranosyl)purine

Modify Date: 2024-01-09 16:32:02

6-Methoxy-9-(2-C-Methyl-beta-D-ribofuranosyl)purine Structure
6-Methoxy-9-(2-C-Methyl-beta-D-ribofuranosyl)purine structure
 Common Name 6-Methoxy-9-(2-C-Methyl-beta-D-ribofuranosyl)purine
CAS Number 565450-78-4 Molecular Weight 296.28
Density N/A Boiling Point N/A
Molecular Formula C12H16N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 6-Methoxy-9-(2-C-Methyl-beta-D-ribofuranosyl)purine


2′-C-Methyl-6-O-methylinosine is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia[1][2].

 Names

Name (2R,3R,4R,5R)-5-Hydroxymethyl-2-(6-methoxy-purin-9-yl)-3-methyl-tetrahydro-furan-3,4-diol

  Biological Activity

Description 2′-C-Methyl-6-O-methylinosine is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia[1][2].
Related Catalog
References

[1]. Virág L, Szabó C. Purines inhibit poly(ADP-ribose) polymerase activation and modulate oxidant-induced cell death. FASEB J. 2001 Jan;15(1):99-107.  

[2]. Saugstad OD. Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production. Pediatr Res. 1988 Feb;23(2):143-50.  

 Chemical & Physical Properties

Molecular Formula C12H16N4O5
Molecular Weight 296.28
Exact Mass 296.11200
PSA 122.75000
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Chemsrc provides CAS#:565450-78-4 MSDS, density, melting point, boiling point, structure, etc. Its name is 6-Methoxy-9-(2-C-Methyl-beta-D-ribofuranosyl)purine>> amp version: 6-Methoxy-9-(2-C-Methyl-beta-D-ribofuranosyl)purine

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