Boc-GABA-OH

Modify Date: 2024-01-02 16:00:28

Boc-GABA-OH Structure
Boc-GABA-OH structure
Common Name Boc-GABA-OH
CAS Number 57294-38-9 Molecular Weight 203.236
Density 1.1±0.1 g/cm3 Boiling Point 78-82 ºC
Molecular Formula C9H17NO4 Melting Point 55-59 °C
MSDS Chinese USA Flash Point 113 ºC

 Use of Boc-GABA-OH


Boc-GABA-OH is a PROTAC linker which can be used to synthesis UNC6852, an EED-targeted PROTAC[1].

 Names

Name 4-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
Synonym More Synonyms

 Boc-GABA-OH Biological Activity

Description Boc-GABA-OH is a PROTAC linker which can be used to synthesis UNC6852, an EED-targeted PROTAC[1].
Related Catalog
Target

Alkyl/ether

References

[1]. Potjewyd F, et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Cell Chem Biol. 2020 Jan 16;27(1):47-56.e15.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 78-82 ºC
Melting Point 55-59 °C
Molecular Formula C9H17NO4
Molecular Weight 203.236
Flash Point 113 ºC
Exact Mass 203.115753
PSA 75.63000
LogP 0.77
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.476
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi
Risk Phrases 44-36/37/38
Safety Phrases S37/39-S26
RIDADR NONH for all modes of transport
WGK Germany 3

 Synonyms

4-[(1,1-dimethylethoxycarbonyl)amino]butanoic acid
4-Amino-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoic acid
N-Boc-g-aminobutyric Acid
Glutamic acid, 1-(1,1-dimethylethyl) ester
Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-
Boc-GABA-OH
MFCD00037313
4-[(tert-butoxycarbonyl)amino]butanoic acid
4-(tert-butyloxycarbonylamino)butyric acid
4-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid
4-[(tert-butoxy)carbonylamino]butanoic acid
butanoic acid, 4-[[(1E)-(1,1-dimethylethoxy)hydroxymethylene]amino]-
4-(Boc-amino)butyric acid
Boc-GABA
N-Boc-gamma-aminobutyric acid
N-(tert-butyloxycarbonyl)-4-aminobutyric acid
4-(tert-Butoxycarbonylamino)butyric acid
N-Boc-γ-aminobutyric acid
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Price: ¥550/100 mg

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