[D-Trp6]-LH-RH

Modify Date: 2024-01-02 16:34:35

[D-Trp6]-LH-RH structure	Common Name	[D-Trp6]-LH-RH
	CAS Number	57773-63-4	Molecular Weight	1311.449
	Density	1.5±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₆₄H₈₂N₁₈O₁₃	Melting Point	N/A
	MSDS	USA	Flash Point	N/A
	Symbol	GHS08	Signal Word	Danger

Use of [D-Trp6]-LH-RH Triptorelin is a GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferationIn vivo: (1) Triptorelin can improve the pregnancy rate by 12% to 15% in ewes6 and downregulate ovarian GnRHR-I expression of female rats, especially in late-growing follicles.(2) Triptorelin immunity blocked EET and UWT, inhibited uterine growth and development and enhance the expression levels s of ESR1, LHR, and FSHR proteins.
Effect of [D-Trp6]-LH-RH

Name	triptorelin
Synonym	More Synonyms

Description	Triptorelin is a GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferationIn vivo: (1) Triptorelin can improve the pregnancy rate by 12% to 15% in ewes6 and downregulate ovarian GnRHR-I expression of female rats, especially in late-growing follicles.(2) Triptorelin immunity blocked EET and UWT, inhibited uterine growth and development and enhance the expression levels s of ESR1, LHR, and FSHR proteins.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GNRH Receptor Research Areas >> Cancer Peptides
References	[1]. Wei S et al. Triptorelin and cetrorelix induce immune responses and affect uterine development and expressions of genes and proteins of ESR1, LHR, and FSHR of mice. Immunopharmacol Immunotoxicol. 2016 Jun;38(3):197-204.

Density	1.5±0.1 g/cm3
Molecular Formula	C₆₄H₈₂N₁₈O₁₃
Molecular Weight	1311.449
Exact Mass	1310.630859
PSA	487.92000
LogP	-0.41
Index of Refraction	1.723
Storage condition	−20°C

Symbol	GHS08
Signal Word	Danger
Hazard Statements	H360
Precautionary Statements	P201-P308 + P313
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T: Toxic;
Risk Phrases	R60
Safety Phrases	53-22-36/37/39-45
RIDADR	NONH for all modes of transport
WGK Germany	3

Changes in the size of rectovaginal endometriotic nodules infiltrating the rectum during hormonal therapies.

Arch. Gynecol. Obstet. 287(3) , 447-53, (2013)

To evaluate the changes in the volume of rectovaginal endometriotic nodules infiltrating the rectum during 12-month treatment with hormonal therapies.This prospective, non-randomized, self-controlled ...

Gonadotropin-releasing hormone agonist for the prevention of chemotherapy-induced ovarian failure in patients with lymphoma: 1-year follow-up of a prospective randomized trial.

J. Clin. Oncol. 31(7) , 903-9, (2013)

To assess the efficacy of gonadotropin-releasing hormone agonist (GnRHa) in preventing chemotherapy-induced ovarian failure in patients treated for Hodgkin or non-Hodgkin lymphoma within the setting o...

Adjuvant exemestane with ovarian suppression in premenopausal breast cancer.

N. Engl. J. Med. 371(2) , 107-18, (2014)

Adjuvant therapy with an aromatase inhibitor improves outcomes, as compared with tamoxifen, in postmenopausal women with hormone-receptor-positive breast cancer.In two phase 3 trials, we randomly assi...

5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolylglycinamide

triptorelinum

triptorelinum [INN_la]

Glycinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolyl-

triptoreline

TRIPORELIN

MFCD00167541

triptorelina

TRIPTORELIN AMIDE

UNII:9081Y98W2V

Triptorelin

TRIPTORELIN PAMOATE

Decapeptyl

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: [D-Trp6]-LH-RH
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Triptorelin
Price: $250.0/100mg $500.0/250mg $1000.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Triptorelin
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Triptorelin Pamoate
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Taiwan Oyi peptide Co. Ltd
China
Product Name:
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Delivery: 1 Day
Contact: Vinnie
Email: Jamie@api-made.com

Get all suppliers and price by the below link:

[D-Trp6]-LH-RH suppliers

Price: $60/1mg

Reference only. check more [D-Trp6]-LH-RH price

[D-Trp6]-LH-RH

Use of [D-Trp6]-LH-RH

Effect of [D-Trp6]-LH-RH

Names

[D-Trp6]-LH-RH Biological Activity

Chemical & Physical Properties

Safety Information

Articles43

Synonyms