9-[3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-3H-purin-6-one

Modify Date: 2024-09-29 11:24:44

9-[3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-3H-purin-6-one Structure
9-[3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-3H-purin-6-one structure
Common Name 9-[3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-3H-purin-6-one
CAS Number 58004-19-6 Molecular Weight 284.29
Density 2.07g/cm3 Boiling Point 708ºC at 760mmHg
Molecular Formula C10H12N4O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 9-[3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-3H-purin-6-one


4’-Thioinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 9-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)-3,9-dihydro-6H-purin-6-one

  Biological Activity

Description 4’-Thioinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.07g/cm3
Boiling Point 708ºC at 760mmHg
Molecular Formula C10H12N4O4S
Molecular Weight 284.29
Exact Mass 284.05800
PSA 149.56000
Index of Refraction 1.935