CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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RB5935000
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CHEMICAL NAME :
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6a-alpha-Noraporphine-2,9-diol, 1,10-dimethoxy-
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CAS REGISTRY NUMBER :
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5890-18-6
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LAST UPDATED :
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198208
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C18-H19-N-O4
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MOLECULAR WEIGHT :
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313.38
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WISWESSER LINE NOTATION :
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T C6666 1A Q KM&TT&J EO1 FQ PQ QO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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450 mg/kg
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TOXIC EFFECTS :
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Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes
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REFERENCE :
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APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 38,537,1980
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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170 mg/kg
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TOXIC EFFECTS :
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Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes
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REFERENCE :
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APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 38,537,1980
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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90 mg/kg
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TOXIC EFFECTS :
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Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes
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REFERENCE :
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APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 38,537,1980
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CAS#:475-81-0
