Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Laurolitsine
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

BioBioPha
China
Product Name: Laurolitsine
Price: ￥Inquiry/5mg
Purity: 98.0%
Stocking Period: 10 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Laurolitsine
Price: ￥1600.0/5mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Laurolitsine
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

5890-18-6

5890-18-6 structure

5890-18-6 structure

Name: Laurolitsine
Chemical Name: laurolistine
CAS Number: 5890-18-6
Molecular Formula: C₁₈H₁₉NO₄
Molecular Weight: 313.348
Catalog: Natural product Alkaloid
Create Date: 2018-05-24 08:00:00
Modify Date: 2024-01-12 16:10:03
Laurolitsine ((+)-Norboldine) is an alkaloid isolated from the leaves of Peumus boldus Molina[1].

Name	laurolistine
Synonyms	Norisoboidine (6aS)-1,10-Dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol Norboldine laurolistine LAUROLITSINE 4H-Dibenzo[de,g]quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-, (6aS)-

Description	Laurolitsine ((+)-Norboldine) is an alkaloid isolated from the leaves of Peumus boldus Molina[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Teng CM, et al. Antiplatelet effects of some aporphine and phenanthrene alkaloids in rabbits and man. J Pharm Pharmacol. 1997 Jul;49(7):706-11.

Density	1.3±0.1 g/cm3
Boiling Point	553.0±50.0 °C at 760 mmHg
Melting Point	138-140ºC
Molecular Formula	C₁₈H₁₉NO₄
Molecular Weight	313.348
Flash Point	288.3±30.1 °C
Exact Mass	313.131409
PSA	70.95000
LogP	1.43
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.643
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RB5935000

CHEMICAL NAME :: 6a-alpha-Noraporphine-2,9-diol, 1,10-dimethoxy-

CAS REGISTRY NUMBER :: 5890-18-6

LAST UPDATED :: 198208

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C18-H19-N-O4

MOLECULAR WEIGHT :: 313.38

WISWESSER LINE NOTATION :: T C6666 1A Q KM&TT&J EO1 FQ PQ QO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 450 mg/kg

TOXIC EFFECTS :: Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 38,537,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 170 mg/kg

TOXIC EFFECTS :: Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 38,537,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 90 mg/kg

TOXIC EFFECTS :: Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 38,537,1980

Precursor 0
DownStream 1
475-81-0