Di(N-succinimidyl)adipate structure
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Common Name | Di(N-succinimidyl)adipate | ||
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CAS Number | 59156-70-6 | Molecular Weight | 340.28500 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C14H16N2O8 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Di(N-succinimidyl)adipateDi(N-succinimidyl)adipate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
Name | bis(2,5-dioxopyrrolidin-1-yl) hexanedioate |
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Synonym | More Synonyms |
Description | Di(N-succinimidyl)adipate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
Alkyl-Chain |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Molecular Formula | C14H16N2O8 |
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Molecular Weight | 340.28500 |
Exact Mass | 340.09100 |
PSA | 127.36000 |
~91% Di(N-succinimid... CAS#:59156-70-6 |
Literature: Mishra, Narendra Kumar; Joshi, Khashti Ballabh; Verma, Sandeep Molecular Pharmaceutics, 2013 , vol. 10, # 10 p. 3903 - 3912 |
Precursor 2 | |
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DownStream 0 |
adipic acid di-N-hydroxysuccinimide ester |
di-(N-hydroxysuccinimidyl) adipate ester |
bis(N-hydroxysuccinimidyl) adipate |
disuccinimidyl adipate |
bis(N-hydroxysuccinimidyl) adipic acid diester |
Di(N-succinimidyl) adipate |
adipic acid bis(succinimidyl) ester |
2,5-Pyrrolidinedione,1,1'-[(1,6-dioxo-1,6-hexanediyl)bis(oxy)]bis |