FQI1

Modify Date: 2024-01-05 10:48:16

FQI1 Structure
FQI1 structure
Common Name FQI1
CAS Number 599151-35-6 Molecular Weight 311.33
Density N/A Boiling Point N/A
Molecular Formula C18H17NO4 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger

 Use of FQI1


FQI1 is a Late SV40 Factor (LSF) inhibitor. FQI1 inhibits cell proliferation, with IC50s of 3, 0.79, 6.3 μM for NIH/3T3, HeLa, A549 cells. FQI1 can be used for cancer research[1].

 Names

Name 8-(2-Ethoxyphenyl)-7,8-dihydro[1,3]dioxolo[4,5-g]quinolin-6(5H)-o ne
Synonym More Synonyms

 FQI1 Biological Activity

Description FQI1 is a Late SV40 Factor (LSF) inhibitor. FQI1 inhibits cell proliferation, with IC50s of 3, 0.79, 6.3 μM for NIH/3T3, HeLa, A549 cells. FQI1 can be used for cancer research[1].
Related Catalog
References

[1]. Ulla Hansen, et al. Inhibitors of late sv40 factor (lsf) as cancer chemotherapeutics. WO2012050985.

 Chemical & Physical Properties

Molecular Formula C18H17NO4
Molecular Weight 311.33
Exact Mass 311.11600
PSA 60.28000
LogP 3.37320

 Safety Information

Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger
Hazard Statements H301-H400
Precautionary Statements P273-P301 + P310
RIDADR UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all

 Synthetic Route

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FQI1 Structure

FQI1

CAS#:599151-35-6

Literature: TRUSTEES OF BOSTON UNIVERSITY; SCHAUS, Scott, E.; HANSEN, Ulla; BISHOP, Joshua, A. Patent: WO2013/52465 A1, 2013 ;

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FQI1 Structure

FQI1

CAS#:599151-35-6

Literature: TRUSTEES OF BOSTON UNIVERSITY; SCHAUS, Scott, E.; HANSEN, Ulla; BISHOP, Joshua, A. Patent: WO2013/52465 A1, 2013 ;

 Synonyms

8-(2-chloro-benzoyloxy)-7-nitro-quinoline
o-Chlorobenzoic acid 7-nitro-8-quinolyl ester
8-(2-ethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one
BENZOIC ACID,o-CHLORO-,7-NITRO-8-QUINOLYL ESTER
8-Quinolinol,7-nitro-,o-chlorobenzoate
7-nitroquinolin-8-yl 2-chlorobenzoate
FQI1
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