599151-35-6
599151-35-6 structure
- Name: FQI1
- Chemical Name: 8-(2-Ethoxyphenyl)-7,8-dihydro[1,3]dioxolo[4,5-g]quinolin-6(5H)-o ne
- CAS Number: 599151-35-6
- Molecular Formula: C18H17NO4
- Molecular Weight: 311.33
- Catalog: Research Areas Cancer
- Create Date: 2017-01-10 20:28:39
- Modify Date: 2024-01-05 10:48:16
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FQI1 is a Late SV40 Factor (LSF) inhibitor. FQI1 inhibits cell proliferation, with IC50s of 3, 0.79, 6.3 μM for NIH/3T3, HeLa, A549 cells. FQI1 can be used for cancer research[1].
| Name | 8-(2-Ethoxyphenyl)-7,8-dihydro[1,3]dioxolo[4,5-g]quinolin-6(5H)-o ne |
|---|---|
| Synonyms |
8-(2-chloro-benzoyloxy)-7-nitro-quinoline
o-Chlorobenzoic acid 7-nitro-8-quinolyl ester 8-(2-ethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one BENZOIC ACID,o-CHLORO-,7-NITRO-8-QUINOLYL ESTER 8-Quinolinol,7-nitro-,o-chlorobenzoate 7-nitroquinolin-8-yl 2-chlorobenzoate FQI1 |
| Description | FQI1 is a Late SV40 Factor (LSF) inhibitor. FQI1 inhibits cell proliferation, with IC50s of 3, 0.79, 6.3 μM for NIH/3T3, HeLa, A549 cells. FQI1 can be used for cancer research[1]. |
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| Related Catalog | |
| References |
[1]. Ulla Hansen, et al. Inhibitors of late sv40 factor (lsf) as cancer chemotherapeutics. WO2012050985. |
| Molecular Formula | C18H17NO4 |
|---|---|
| Molecular Weight | 311.33 |
| Exact Mass | 311.11600 |
| PSA | 60.28000 |
| LogP | 3.37320 |
| Symbol |
GHS06, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H400 |
| Precautionary Statements | P273-P301 + P310 |
| RIDADR | UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all |
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599151-35-6 |
| Literature: TRUSTEES OF BOSTON UNIVERSITY; SCHAUS, Scott, E.; HANSEN, Ulla; BISHOP, Joshua, A. Patent: WO2013/52465 A1, 2013 ; |
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~%
599151-35-6 |
| Literature: TRUSTEES OF BOSTON UNIVERSITY; SCHAUS, Scott, E.; HANSEN, Ulla; BISHOP, Joshua, A. Patent: WO2013/52465 A1, 2013 ; |
