Aurin

Modify Date: 2024-01-11 19:53:40

Aurin Structure
Aurin structure
Common Name Aurin
CAS Number 603-45-2 Molecular Weight 290.31
Density 1.3±0.1 g/cm3 Boiling Point 543.0±50.0 °C at 760 mmHg
Molecular Formula C19H14O3 Melting Point ca. 308ºC (decomposes)
MSDS USA Flash Point 296.2±26.6 °C

 Use of Aurin


Rosolic Acid is an activator of Nrf2, as well as its downstream targets. Rosolic Acid increases the levels of angiogenic factors, decreases inflammation (TNF-α and IL-1β) and apoptotic markers (CXCL10 and CCL2). Rosolic Acid restores the function of pancreatic cells and protects endothelial cells (ECs) from endoplasmic reticulum stressed[1].

 Names

Name 4-[bis(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one
Synonym More Synonyms

 Aurin Biological Activity

Description Rosolic Acid is an activator of Nrf2, as well as its downstream targets. Rosolic Acid increases the levels of angiogenic factors, decreases inflammation (TNF-α and IL-1β) and apoptotic markers (CXCL10 and CCL2). Rosolic Acid restores the function of pancreatic cells and protects endothelial cells (ECs) from endoplasmic reticulum stressed[1].
Related Catalog
References

[1]. Amin KN, et al. Effect of Rosolic acid on endothelial dysfunction under ER stress in pancreatic microenvironment. Free Radic Res. 2021 Jun;55(6):698-713.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 543.0±50.0 °C at 760 mmHg
Melting Point ca. 308ºC (decomposes)
Molecular Formula C19H14O3
Molecular Weight 290.31
Flash Point 296.2±26.6 °C
Exact Mass 290.094299
PSA 57.53000
LogP 3.15
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.691
Storage condition Store at room temperature.
Water Solubility Solubility Practically insoluble in water, benzene; freely soluble in ethanol

 Safety Information

Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2914501900

 Synthetic Route

 Customs

HS Code 2914501900
Summary 2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Articles15

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Screening of natural and synthetic drugs against Trypanosoma cruzi. 1. Establishing a structure/activity relationship.

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The activity of 45 compounds against bloodstream forms of Trypanosoma cruzi was investigated. The aim was to consider new agents which might subsequently be assayed for chemoprophylaxis in donated blo...

Crystal structure analysis of oxidized Pseudomonas aeruginosa azurin at pH 5.5 and pH 9.0. A pH-induced conformational transition involves a peptide bond flip.

J. Mol. Biol. 221(3) , 765-72, (1991)

The X-ray crystal structure of recombinant wild-type azurin from Pseudomonas aeruginosa was determined by difference Fourier techniques using phases derived from the structure of the mutant His35Leu. ...

 Synonyms

4-(p,p'-Dihydroxybenzhydrylidene)-2,5-cyclohexadien-1-one
Aurin No. 555
MFCD00001624
2,5-Cyclohexadien-1-one, 4-[bis(4-hydroxyphenyl)methylene]-
EINECS 210-041-8
4-[bis(4-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one
Aurin
4-<bis(4-hydroxyphenyl)methylene>-2,5-cyclohexadienone
2,5-Cyclohexadien-1-one, 4-(bis(4-hydroxyphenyl)methylene)-
rosolic acid
4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadien-1-one
Corallin Spirit Soluble
4,4'-Dihydroxyfuchsone
4-(Bis(p-hydroxyphenyl)methylene)cyclohexa-2,5-dien-1-one
4-[bis(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one
Aurine
Corallin
p-Rosolic acid
Spirit Aurine
4-[bis-(4-hydroxyphenyl)methylene]-cyclohexa-2,5-dienone
Rosalic Acid
CI 43800
Pararosolic Acid
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Price: ¥178/25g

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