3’-O-Methyluridine

Modify Date: 2024-01-12 16:41:17

3’-O-Methyluridine structure	Common Name	3’-O-Methyluridine
	CAS Number	6038-59-1	Molecular Weight	258.23
	Density	1.53g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₄N₂O₆	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of 3’-O-Methyluridine

3’-O-Methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	4-[1-[(2-methylphenyl)methyl]benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine
Synonym	More Synonyms

Description	3’-O-Methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.53g/cm3
Molecular Formula	C₁₀H₁₄N₂O₆
Molecular Weight	258.23
Exact Mass	258.08500
PSA	113.78000
Index of Refraction	1.611

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

N/A

CAS#:1213263-37-6

~99%

3’-O-Methyluridine

CAS#:6038-59-1

Literature: Aleiwi, Bilal A.; Kurosu, Michio Tetrahedron Letters, 2012 , vol. 53, # 29 p. 3758 - 3762

3'-O-methyl-5'-...

CAS#:174020-29-2

~83%

3’-O-Methyluridine

CAS#:6038-59-1

Literature: Cramer, Hagen; Pfleiderer, Wolfgang Helvetica Chimica Acta, 1996 , vol. 79, # 8 p. 2114 - 2136

diazomethane

CAS#:186581-53-3

Uridine

CAS#:58-96-8

3’-O-Methyluridine

CAS#:6038-59-1

2'-O-Methyluridine

CAS#:2140-76-3

Literature: Heikkilae, Jarmo; Bjoerkman, Sven; Oeberg, Bo; Chattopadhyaya, Jyoti Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1982 , vol. 36, # 10 p. 715 - 718

Precursor 2
CAS#:186581-53-3 diazomethane CAS#:58-96-8 Uridine
DownStream 0

Differentiation of 2'-O- and 3'-O-methylated ribonucleosides by tandem mass spectrometry.

J. Am. Soc. Mass Spectrom. 17 , 1096-1099, (2006)

Recent studies revealed that the 3'-terminal nucleotides in plant microRNAs were methylated on the ribose at the 2' or 3' hydroxyl groups. Here we examined the fragmentation of the electrospray-produc...

3'-O-Methyl-uridin

O3'-methyl-uridine

3'-O-methyluridine