Ethyl 7-hydroxy-2-oxo-2H-chromene-3-carboxylate structure
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Common Name | Ethyl 7-hydroxy-2-oxo-2H-chromene-3-carboxylate | ||
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CAS Number | 6093-71-6 | Molecular Weight | 234.205 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 448.3±45.0 °C at 760 mmHg | |
Molecular Formula | C12H10O5 | Melting Point | 170.0 to 174.0 °C | |
MSDS | Chinese USA | Flash Point | 178.7±22.2 °C |
Use of Ethyl 7-hydroxy-2-oxo-2H-chromene-3-carboxylateY29 is a potent PFKFB3 inhibitor with an IC50 of 0.183 µM, and acts as a competitive inhibitor against Fru-6-P with a Ki of 0.094 µM. Y29 also inhibits the HeLa cell growth with a GI50 of 2.7 µM[1]. |
Name | ethyl 7-hydroxy-2-oxochromene-3-carboxylate |
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Synonym | More Synonyms |
Description | Y29 is a potent PFKFB3 inhibitor with an IC50 of 0.183 µM, and acts as a competitive inhibitor against Fru-6-P with a Ki of 0.094 µM. Y29 also inhibits the HeLa cell growth with a GI50 of 2.7 µM[1]. |
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Related Catalog | |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 448.3±45.0 °C at 760 mmHg |
Melting Point | 170.0 to 174.0 °C |
Molecular Formula | C12H10O5 |
Molecular Weight | 234.205 |
Flash Point | 178.7±22.2 °C |
Exact Mass | 234.052826 |
PSA | 76.74000 |
LogP | 1.85 |
Appearance of Characters | white to beige |
Vapour Pressure | 0.0±1.1 mmHg at 25°C |
Index of Refraction | 1.598 |
Storage condition | −20°C |
Water Solubility | DMSO: soluble5mg/mL, clear (warmed) |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2932209090 |
Precursor 8 | |
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DownStream 10 | |
HS Code | 2932209090 |
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Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
3-carboethoxy-7-hydroxycoumarin |
MFCD00017641 |
2H-1-Benzopyran-3-carboxylic acid, 7-hydroxy-2-oxo-, ethyl ester |
7-Hydroxy-2-oxo-2H-chromene-3-carboxylic acid ethyl ester |
7-Hydroxycoumarin-3-carboxylic acid ethyl ester |
ethyl 7-hydroxy-2-oxo-2H-[1]benzopyran-3-carboxylate |
3-CARBETHOXYUMBELIFERONE |
Ethyl 7-hydroxy-2-oxo-2H-chromene-3-carboxylate |
Ethyl 7-hydroxy-2-oxo-2H-1-benzopyran-3-carboxylate |
ethyl 7-hydroxycoumarin-3-carboxylate |
7-hydroxy-2-oxo-2H-1-benzopyran-3-carboxylic acid ethyl ester |
7-HYDROXY-2-OXO-CHROMENE-3-CARBOXYLIC ACID ETHYL ESTER |
YZ9 |
1gcz |
3-carbethoxy-7-hydroxycoumarin |