DC4

Modify Date: 2024-01-15 07:51:23

DC4 Structure
DC4 structure
Common Name DC4
CAS Number 615538-48-2 Molecular Weight 718.12
Density N/A Boiling Point N/A
Molecular Formula C34H29ClN5O7PS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DC4


DC4, a ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4 can be used for the targeted treatment of cancer[1].

 Names

Name DC4

 DC4 Biological Activity

Description DC4, a ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4 can be used for the targeted treatment of cancer[1].
Related Catalog
In Vitro DC4 can be conjugated to the humanized monoclonal antibody huB4 and huC242 by a linker SPP, SPDB, and SMCC to form huB4-SPP-DC44, huC242-SPDB-DC4, huC242-SPP-DC4, and huC242-SMCC-DC4[1].
References

[1]. Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer. J Med Chem. 2012 Jan 26;55(2):766-82.

 Chemical & Physical Properties

Molecular Formula C34H29ClN5O7PS
Molecular Weight 718.12