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615538-48-2

615538-48-2 structure
615538-48-2 structure
  • Name: DC4
  • Chemical Name: DC4
  • CAS Number: 615538-48-2
  • Molecular Formula: C34H29ClN5O7PS
  • Molecular Weight: 718.12
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Cytotoxin
  • Create Date: 2020-01-23 18:13:51
  • Modify Date: 2024-01-15 07:51:23
  • DC4, a ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4 can be used for the targeted treatment of cancer[1].

Name DC4
Description DC4, a ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4 can be used for the targeted treatment of cancer[1].
Related Catalog
In Vitro DC4 can be conjugated to the humanized monoclonal antibody huB4 and huC242 by a linker SPP, SPDB, and SMCC to form huB4-SPP-DC44, huC242-SPDB-DC4, huC242-SPP-DC4, and huC242-SMCC-DC4[1].
References

[1]. Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer. J Med Chem. 2012 Jan 26;55(2):766-82.

Molecular Formula C34H29ClN5O7PS
Molecular Weight 718.12