7-deazaguanosine

Modify Date: 2024-01-04 16:16:21

7-deazaguanosine Structure
7-deazaguanosine structure
Common Name 7-deazaguanosine
CAS Number 62160-23-0 Molecular Weight 282.25
Density 2.06g/cm3 Boiling Point 668.3ºC at 760mmHg
Molecular Formula C11H14N4O5 Melting Point >250ºC dec
MSDS N/A Flash Point 358ºC

 Use of 7-deazaguanosine


7-Deazaguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 7-deazaguanosine
Synonym More Synonyms

 7-deazaguanosine Biological Activity

Description 7-Deazaguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.06g/cm3
Boiling Point 668.3ºC at 760mmHg
Melting Point >250ºC dec
Molecular Formula C11H14N4O5
Molecular Weight 282.25
Flash Point 358ºC
Exact Mass 282.09600
PSA 146.62000
Index of Refraction 1.874

 Synonyms

7-Desazaguanosin
PELDESINE
BCX-34