Br-C10-methyl ester

Modify Date: 2024-01-10 18:00:15

Br-C10-methyl ester Structure
Br-C10-methyl ester structure
Common Name Br-C10-methyl ester
CAS Number 6287-90-7 Molecular Weight 279.21400
Density 1.157 g/mL at 25ºC(lit.) Boiling Point 115ºC0.04 mm Hg(lit.)
Molecular Formula C12H23BrO2 Melting Point 13°C(lit.)
MSDS USA Flash Point >230 °F

 Use of Br-C10-methyl ester


Br-C10-methyl ester is a PROTAC linker, which refers to the alkyl/ether composition. Br-C10-methyl ester is used in the synthesis of a series of PROTACs (MS432).  PROTACs contain two different ligands connected by a linker; one is the VHL ligand portion and the other is for the target protein[1].

 Names

Name methyl 11-bromoundecanoate
Synonym More Synonyms

 Br-C10-methyl ester Biological Activity

Description Br-C10-methyl ester is a PROTAC linker, which refers to the alkyl/ether composition. Br-C10-methyl ester is used in the synthesis of a series of PROTACs (MS432).  PROTACs contain two different ligands connected by a linker; one is the VHL ligand portion and the other is for the target protein[1].
Related Catalog
Target

Alkyl/ether

References

[1]. Wei J, et al. Discovery of a First-in-Class Mitogen-Activated Protein Kinase Kinase 1/2 Degrader.J Med Chem. 2019 Dec 12;62(23):10897-10911.

 Chemical & Physical Properties

Density 1.157 g/mL at 25ºC(lit.)
Boiling Point 115ºC0.04 mm Hg(lit.)
Melting Point 13°C(lit.)
Molecular Formula C12H23BrO2
Molecular Weight 279.21400
Flash Point >230 °F
Exact Mass 278.08800
PSA 26.30000
LogP 4.06520
Index of Refraction n20/D 1.465(lit.)

 Safety Information

Personal Protective Equipment Eyeshields;Gloves
RIDADR NONH for all modes of transport
HS Code 2915900090

 Synthetic Route

 Customs

HS Code 2915900090
Summary 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

 Articles3

More Articles
Versatile synthesis of phenoxydiazirine-based fatty acid analogues and photoreactive galactosylceramide.

Bioorg. Med. Chem. Lett. 12(1) , 89-91, (2002)

A versatile synthesis of diazirine-based photoreactive fatty acid analogues is reported. The key step is phenoxy alkylation of diazirine with halo alkyl acid esters. The conditions described will be a...

Studies on ω-Oxidation of Fatty Acids in vitro. KAMEI S, et al.

J. Biochem. 56(1) , 72-76, (1964)

A Three Step Synthesis of 11-Cycloheptylundecanoic Acid, a Component of the Thermoacidophile Alicyclobacillus cycloheptanicus. Hassarajani SA and Mamdapur VR.

Molecules 3(2) , 41-43, (1998)

 Synonyms

MFCD00045047
methyl 11-bromoundecan-1-oate
11-bromo-undecanoic acid methyl ester
11-Brom-undecansaeure-methylester
methyl 11-bromoundecanate
11-Brom-undecylsaeure-methylester
Top Suppliers:I want be here


Get all suppliers and price by the below link:

Br-C10-methyl ester suppliers

Br-C10-methyl ester price