6287-90-7
6287-90-7 structure
- Name: Br-C10-methyl ester
- Chemical Name: methyl 11-bromoundecanoate
- CAS Number: 6287-90-7
- Molecular Formula: C12H23BrO2
- Molecular Weight: 279.21400
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-10-03 11:39:32
- Modify Date: 2024-01-10 18:00:15
-
Br-C10-methyl ester is a PROTAC linker, which refers to the alkyl/ether composition. Br-C10-methyl ester is used in the synthesis of a series of PROTACs (MS432). PROTACs contain two different ligands connected by a linker; one is the VHL ligand portion and the other is for the target protein[1].
| Name | methyl 11-bromoundecanoate |
|---|---|
| Synonyms |
MFCD00045047
methyl 11-bromoundecan-1-oate 11-bromo-undecanoic acid methyl ester 11-Brom-undecansaeure-methylester methyl 11-bromoundecanate 11-Brom-undecylsaeure-methylester |
| Description | Br-C10-methyl ester is a PROTAC linker, which refers to the alkyl/ether composition. Br-C10-methyl ester is used in the synthesis of a series of PROTACs (MS432). PROTACs contain two different ligands connected by a linker; one is the VHL ligand portion and the other is for the target protein[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl/ether |
| References |
| Density | 1.157 g/mL at 25ºC(lit.) |
|---|---|
| Boiling Point | 115ºC0.04 mm Hg(lit.) |
| Melting Point | 13°C(lit.) |
| Molecular Formula | C12H23BrO2 |
| Molecular Weight | 279.21400 |
| Flash Point | >230 °F |
| Exact Mass | 278.08800 |
| PSA | 26.30000 |
| LogP | 4.06520 |
| Index of Refraction | n20/D 1.465(lit.) |
| Personal Protective Equipment | Eyeshields;Gloves |
|---|---|
| RIDADR | NONH for all modes of transport |
| HS Code | 2915900090 |
| Precursor 9 | |
|---|---|
| DownStream 10 | |
![[(11-Iodoundecyl)oxy]trimethylsilane structure](https://image.chemsrc.com/caspic/404/26305-84-0.png)
| HS Code | 2915900090 |
|---|---|
| Summary | 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0% |