6-chlorohexyl bromide

Modify Date: 2024-01-02 20:14:40

6-chlorohexyl bromide Structure
6-chlorohexyl bromide structure
Common Name 6-chlorohexyl bromide
CAS Number 6294-17-3 Molecular Weight 199.52
Density 1.3±0.1 g/cm3 Boiling Point 217.4±8.0 °C at 760 mmHg
Molecular Formula C6H12BrCl Melting Point N/A
MSDS Chinese USA Flash Point 101.1±0.0 °C

 Use of 6-chlorohexyl bromide


1-Bromo-6-chlorohexane is a PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name 1-Bromo-6-chlorohexane
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 217.4±8.0 °C at 760 mmHg
Molecular Formula C6H12BrCl
Molecular Weight 199.52
Flash Point 101.1±0.0 °C
Exact Mass 197.981079
LogP 3.49
Vapour Pressure 0.2±0.4 mmHg at 25°C
Index of Refraction 1.470

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard Codes Xn
Risk Phrases R36/37/38
Safety Phrases S23-S24/25
RIDADR 2810
WGK Germany 3
Packaging Group III
Hazard Class 6.1(b)

 Synthetic Route

~96%

6-chlorohexyl bromide Structure

6-chlorohexyl b...

CAS#:6294-17-3

Literature: Crosignani, Stefano; Nadal, Brice; Li, Zhengning; Linclau, Bruno Chemical Communications, 2003 , # 2 p. 260 - 261

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6-chlorohexyl bromide Structure

6-chlorohexyl b...

CAS#:6294-17-3

Literature: Journal of Organic Chemistry, , vol. 59, # 9 p. 2616 - 2619

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6-chlorohexyl bromide Structure

6-chlorohexyl b...

CAS#:6294-17-3

Literature: Shin-Etsu Chemical Co., Ltd. Patent: US5880318 A1, 1999 ;

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6-chlorohexyl bromide Structure

6-chlorohexyl b...

CAS#:6294-17-3

Literature: Journal of Organic Chemistry, , vol. 59, # 9 p. 2616 - 2619

 Articles1

More Articles
Preparation of highly functionalized alkylzinc halides from alkyl bromides using Mg, ZnCl2 and LiCl.

Chem. Commun. (Camb.) 46(23) , 4082-4, (2010)

Alkyl bromides bearing various functional groups are smoothly converted to functionalized alkylzinc reagents by the direct insertion of magnesium in the presence of LiCl and ZnCl(2).

 Synonyms

MFCD00001019
1-Bromo-6-chlorohexane
Cl(CH2)6-Br
1-Chloro-6-bromohexane
Hexane, 1-bromo-6-chloro-
1-bromo-6-chloro-hexane
6-chlorohexyl bromide
Hexyl bromide, 6-chloro-
EINECS 228-555-6
1,6-bromochlorohexane
Hexyl bromide,6-chloro
Hexane,1-bromo-6-chloro
6-Bromohexyl Chloride
1-bromo-6-chloro-n-hexane
1-bromo-6-chlorobutane
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