NSC31205
Modify Date: 2024-01-03 16:13:20
NSC31205 structure
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Common Name | NSC31205 | ||
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| CAS Number | 6320-51-0 | Molecular Weight | 235.25900 | |
| Density | 1.391g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C11H9NO3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NSC31205Pim-1/2 kinase inhibitor 1 is an orally active pim-1/2 kinase inhibitor. Pim-1/2 kinase inhibitor 1 blocks the ability of Pim kinases to phosphorylate peptides, and inhibits the pim protein kinase directed phosphorylation of 4E-BP1 and p27Kip1. Pim-1/2 kinase inhibitor 1 can be used in study of cancer, especially prostate cancer[1]. |
| Name | 5-[(4-methoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione |
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| Synonym | More Synonyms |
| Description | Pim-1/2 kinase inhibitor 1 is an orally active pim-1/2 kinase inhibitor. Pim-1/2 kinase inhibitor 1 blocks the ability of Pim kinases to phosphorylate peptides, and inhibits the pim protein kinase directed phosphorylation of 4E-BP1 and p27Kip1. Pim-1/2 kinase inhibitor 1 can be used in study of cancer, especially prostate cancer[1]. |
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| Related Catalog | |
| In Vitro | Pim-1/2 kinase inhibitor 1 (compound D14) (varying concentrations; 48 h) shows cytotoxicity to PC3 cells, with an IC of 11 µM[1]. Cell Cytotoxicity Assay[1] Cell Line: PC3 cells Concentration: varying concentrations Incubation Time: 48 h Result: Inhibited PC3 cells with an IC of 11 µM. |
| References |
| Density | 1.391g/cm3 |
|---|---|
| Molecular Formula | C11H9NO3S |
| Molecular Weight | 235.25900 |
| Exact Mass | 235.03000 |
| PSA | 80.70000 |
| LogP | 2.34790 |
| Index of Refraction | 1.667 |
| Storage condition | -20℃ |
| 5-(4-methoxy-benzylidene)-thiazolidine-2,4-dione |
| 5-(4-methoxybenzylidene)-2,4-thiazolidinedione |
| (Z)-5-(4-methoxybenzylidene)-2,4-thiazolidinedione |
| (Z)-5-4-(methoxybenzylidene)thiazolidine-2,4-dione |
| 2,4-Thiazolidinedione,5-p-methoxybenzylidene |
| (5Z)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione |
| (Z)-5-(4-methoxyphenylmethylene)-2,4-thiazolidinedione |