Amodiaquin dihydrochloride dihydrate
Modify Date: 2024-01-08 18:54:13
Amodiaquin dihydrochloride dihydrate structure
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Common Name | Amodiaquin dihydrochloride dihydrate | ||
|---|---|---|---|---|
| CAS Number | 6398-98-7 | Molecular Weight | 464.81 | |
| Density | N/A | Boiling Point | 535.4ºC at 760 mmHg | |
| Molecular Formula | C20H22ClN3O.2H2O.2HCl | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 277.6ºC | |
Use of Amodiaquin dihydrochloride dihydrateAmodiaquine dihydrochloride dihydrate is a histamine N-methyltransferase inhibitor, used as an antimalarial and anti-inflammatory agent.Target: histamine N-methyltransferaseAmodiaquine has been shown to be more effective than chloroquine in treating chloroquine-resistant Plasmodium falciparum malaria infections and may afford more protection than chloroquine when used as weekly prophylaxis. Amodiaquine is generally well tolerated. |
| Name | amodiaquine hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | Amodiaquine dihydrochloride dihydrate is a histamine N-methyltransferase inhibitor, used as an antimalarial and anti-inflammatory agent.Target: histamine N-methyltransferaseAmodiaquine has been shown to be more effective than chloroquine in treating chloroquine-resistant Plasmodium falciparum malaria infections and may afford more protection than chloroquine when used as weekly prophylaxis. Amodiaquine is generally well tolerated. |
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| Related Catalog |
| Boiling Point | 535.4ºC at 760 mmHg |
|---|---|
| Molecular Formula | C20H22ClN3O.2H2O.2HCl |
| Molecular Weight | 464.81 |
| Flash Point | 277.6ºC |
| PSA | 48.39000 |
| LogP | 6.85620 |
|
Material Safety Data Sheet
Section1. Identification of the substance Product Name: Amodiaquin diHCl dihydrate Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. Section3. Composition/information on ingredients. Ingredient name:Amodiaquin diHCl dihydrate CAS number:6398-98-7 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Store in closed vessels. Storage: Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data No data Melting point: Flash point:No data Density:No data Molecular formula:C20H22ClN3O.2ClH.2H2O Molecular weight:464.8 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen chloride. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xn |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Inhibition of influenza virus replication by targeting broad host cell pathways.
PLoS ONE 9(10) , e110631, (2014) Antivirals that are currently used to treat influenza virus infections target components of the virus which can mutate rapidly. Consequently, there has been an increase in the number of resistant stra... |
| UNII:K6PW2S574L |
| Amodiaquine hydrochloride USP24 |
| Amodiaquin dihydrochloride dihydrate |
| AMODIAQUIN DIHYDROCHLORIDE DIHYDATE |
| MFCD00078857 |
| Amodiaquin hydrochloride dihydrate |
| AMODIAQUIN HYDROCHLORIDE |
| AMODIAQUINE 2HCL DIHYDRATE |
| EINECS 200-706-0 |
| Phenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]-, hydrochloride, hydrate (1:2:2) |
| AMODIAQUIN DIHYDROCHLORIDE |
| AMODIAQUINE HCL |
| 4-[(7-Chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]phenol dihydrochloride dihydrate |
| AMODIAQUINE DIHYDROCHLORIDE |
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- Product Name: Amodiaquin dihydrochloride dihydrate
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- Email: enquiry@dycnchem.com
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