Tetracosane

Modify Date: 2024-01-02 18:14:06

Tetracosane Structure
Tetracosane structure
Common Name Tetracosane
CAS Number 646-31-1 Molecular Weight 338.654
Density 0.8±0.1 g/cm3 Boiling Point 391.1±5.0 °C at 760 mmHg
Molecular Formula C24H50 Melting Point 49-52 °C(lit.)
MSDS Chinese USA Flash Point 234.5±7.2 °C

 Use of Tetracosane


Tetracosane (ALKANE C24) is a natural product that can be found in Acrostichum aureum. Tetracosane hows cytotoxicity and induces Apoptosis. Tetracosane has the potential for the research of peptic ulcer[1].

 Names

Name tetracosane
Synonym More Synonyms

 Tetracosane Biological Activity

Description Tetracosane (ALKANE C24) is a natural product that can be found in Acrostichum aureum. Tetracosane hows cytotoxicity and induces Apoptosis. Tetracosane has the potential for the research of peptic ulcer[1].
Related Catalog
In Vitro Tetracosane (0-250 µM; 24, 48 h) 表现出细胞毒性并以时间依赖性方式诱导细胞凋亡[1]。 Cell Cytotoxicity Assay[1] Cell Line: HT-29, MDA-MB-231, AGS cells Concentration: 0-250 µM Incubation Time: Result: Showed cytotoxicity with IC50s of 128.7, >250, >250 µM for HT-29, MDA-MB-231, AGS cells, respectively. Apoptosis Analysis[1] Cell Line: AGS cells Concentration: 500 µg/mL Incubation Time: 24, 48 h Result: Induced apoptosis with the late apoptosis rate of 10% at 24 h and increased to 20% at 48 h.
References

[1]. Uddin SJ, et al. Evaluation of cytotoxic activity of patriscabratine, tetracosane and various flavonoids isolated from the Bangladeshi medicinal plant Acrostichum aureum. Pharm Biol. 2012 Oct;50(10):1276-80.  

 Chemical & Physical Properties

Density 0.8±0.1 g/cm3
Boiling Point 391.1±5.0 °C at 760 mmHg
Melting Point 49-52 °C(lit.)
Molecular Formula C24H50
Molecular Weight 338.654
Flash Point 234.5±7.2 °C
Exact Mass 338.391266
LogP 13.51
Vapour Pressure 0.0±0.4 mmHg at 25°C
Index of Refraction 1.446

 MSDS

Name: Tetracosane 99% Material Safety Data Sheet
Synonym: None Known
CAS: 646-31-1
Section 1 - Chemical Product MSDS Name:Tetracosane 99% Material Safety Data Sheet
Synonym:None Known

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
646-31-1 Tetracosane 99% 211-474-5
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 646-31-1: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 391 deg C @ 760.00mmHg
Freezing/Melting Point: 49.00 - 52.00 deg C
Autoignition Temperature: Not applicable.
Flash Point: > 110 deg C (> 230.00 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: insoluble
Specific Gravity/Density:
Molecular Formula: C24H50
Molecular Weight: 338.65

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 646-31-1 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Tetracosane - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 646-31-1: No information available.
Canada
CAS# 646-31-1 is listed on Canada's DSL List.
CAS# 646-31-1 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 646-31-1 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes F+
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2901100000

 Synthetic Route

 Customs

HS Code 2901100000
Summary 2901100000 saturated acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

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 Synonyms

tetracosan acid
n-tetracosane
UNII-YQ5H1M1D7I
tetraeicosane
EINECS 211-474-5
MFCD00009352
Tetracosane
Tricosane,methyl
T8752_ALDRICH
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