CLIP 86-100

Modify Date: 2024-01-09 17:01:29

CLIP 86-100 Structure
CLIP 86-100 structure
Common Name CLIP 86-100
CAS Number 648881-58-7 Molecular Weight 1674.10
Density N/A Boiling Point N/A
Molecular Formula C72H128N20O19S3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CLIP 86-100


CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site[1].

 Names

Name CLIP 86-100

 CLIP 86-100 Biological Activity

Description CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site[1].
Related Catalog
References

[1]. van Luijn MM, et al. Class II-associated invariant chain peptide as predictive immune marker in minimal residual disease in acute myeloid leukemia. Oncoimmunology. 2015 Jan 7;3(12):e941737. eCollection 2014 Dec.

[2]. Thayer WP, et al. Class II-associated invariant chain peptide-independent binding of invariant chain to class II MHC molecules. J Immunol. 1999 Feb 1;162(3):1502-9.

 Chemical & Physical Properties

Molecular Formula C72H128N20O19S3
Molecular Weight 1674.10