1-Oxo Ibuprofen
Modify Date: 2024-01-05 18:56:17
1-Oxo Ibuprofen structure
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Common Name | 1-Oxo Ibuprofen | ||
|---|---|---|---|---|
| CAS Number | 65813-55-0 | Molecular Weight | 220.26400 | |
| Density | 1.107g/cm3 | Boiling Point | 377.952ºC at 760 mmHg | |
| Molecular Formula | C13H16O3 | Melting Point | 85-87ºC | |
| MSDS | Chinese USA | Flash Point | 196.555ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 1-Oxo Ibuprofen1-Oxo Ibuprofen (Ibuprofen EP impurity J) is a degradation product and a potential impurity in preparations of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2]. |
| Name | 1-Oxo Ibuprofen |
|---|---|
| Synonym | More Synonyms |
| Description | 1-Oxo Ibuprofen (Ibuprofen EP impurity J) is a degradation product and a potential impurity in preparations of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2]. |
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| Related Catalog | |
| References |
| Density | 1.107g/cm3 |
|---|---|
| Boiling Point | 377.952ºC at 760 mmHg |
| Melting Point | 85-87ºC |
| Molecular Formula | C13H16O3 |
| Molecular Weight | 220.26400 |
| Flash Point | 196.555ºC |
| Exact Mass | 220.11000 |
| PSA | 54.37000 |
| LogP | 2.71340 |
| Index of Refraction | 1.528 |
| Storage condition | -20°C Freezer |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Hazard Codes | Xn |
| Risk Phrases | 22 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2918300090 |
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1-Oxo Ibuprofen CAS#:65813-55-0 |
| Literature: Journal of the American Chemical Society, , vol. 130, # 5 p. 1628 - 1637 |
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1-Oxo Ibuprofen CAS#:65813-55-0 |
| Literature: US6359182 B1, ; Page column 53 ; |
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Detail
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| Literature: Journal of the Chemical Society, Chemical Communications, , # 8 p. 601 - 602 |
| Precursor 1 | |
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| DownStream 0 | |
| HS Code | 2918300090 |
|---|---|
| Summary | 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
| 2-[4-(2-methylpropanoyl)phenyl]propanoic acid |