Punicalagin

Modify Date: 2024-01-02 00:37:19

Punicalagin Structure
Punicalagin structure
Common Name Punicalagin
CAS Number 65995-63-3 Molecular Weight 1084.718
Density 2.1±0.1 g/cm3 Boiling Point N/A
Molecular Formula C48H28O30 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of Punicalagin


Punicalagin is a polyphenol ingredient isolated from Pomegranate (Punica granatum L.) or the leaves of Terminalia catappa L.. Punicalagin is a anti-hepatitis B virus (HBV) agent and has antioxidant, anti-inflammatory, and anticancer effects[1][2][3].

 Names

Name Punicalagin
Synonym More Synonyms

 Punicalagin Biological Activity

Description Punicalagin is a polyphenol ingredient isolated from Pomegranate (Punica granatum L.) or the leaves of Terminalia catappa L.. Punicalagin is a anti-hepatitis B virus (HBV) agent and has antioxidant, anti-inflammatory, and anticancer effects[1][2][3].
Related Catalog
In Vitro Punicalagin (100 mg/ml) induces apoptosis in HT-29, HCT116 colon cells[1].
In Vivo Punicalagin (10 mg/kg) inhibits the edema rate of 58.15% in rats[2].
References

[1]. Seeram NP, et al. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagicacid and a total pomegranate tannin extract are enhanced in combination with otherpolyphenols as found in pomegranate juice. J Nutr Biochem. 2005 Jun;16(6):360-7.

[2]. Lin CC, et al. Effects of punicalagin and punicalin on carrageenan-induced inflammation in rats. Am J Chin Med. 1999;27(3-4):371-6.

[3]. Liu C, et al. Identification of hydrolyzable tannins (punicalagin, punicalin and geraniin) as novel inhibitors of hepatitis B virus covalently closed circular DNA. Antiviral Res. 2016 Oct;134:97-107.

 Chemical & Physical Properties

Density 2.1±0.1 g/cm3
Molecular Formula C48H28O30
Molecular Weight 1084.718
Exact Mass 1084.066528
PSA 518.76000
LogP 2.36
Appearance of Characters faint yellow to dark yellow
Index of Refraction 1.893
Storage condition 2-8°C
Water Solubility methanol: soluble5mg/mL, clear

 Safety Information

Hazard Codes Xi
Safety Phrases 24/25
RIDADR NONH for all modes of transport

 Articles30

More Articles
Effects of pomegranate chemical constituents/intestinal microbial metabolites on CYP1B1 in 22Rv1 prostate cancer cells.

J. Agric. Food Chem. 57(22) , 10636-44, (2009)

The cytochrome P450 enzyme, CYP1B1, is an established target in prostate cancer chemoprevention. Compounds inhibiting CYP1B1 activity are contemplated to exert beneficial effects at three stages of pr...

Biological activities of phenolic compounds isolated from galls of Terminalia chebula Retz. (Combretaceae).

Nat. Prod. Res. 24(20) , 1915-26, (2010)

The aqueous extract of galls from Terminalia chebula Retz. (Combretaceae) was fractionated on Diaion and refractionated on octadecyl silica column. Six phenolic compounds were isolated and identified ...

Inhibition of melanin content by Punicalagins in the super fruit pomegranate (Punica granatum).

J. Cosmet. Sci. 64(6) , 445-53, (2013)

Current efforts to develop effective skin lightening products through the inhibition of melanin production have focused on compounds that inhibit the function and activity of tyrosinase, the rate-limi...

 Synonyms

pulchinenoside b4(rg)
1,2,3,11,12,13-Hexahydroxy-5,10-dioxo-8-[3,4,5,11,17,18,19,22,23,34,35-undecahydroxy-8,14,26,31-tetraoxo-9,13,25,32-tetraoxaheptacyclo[25.8.0.0.0.0.0.0]pentatriaconta- 1(35),2,4,6,15,17,19,21,23,27,29,33-dodecaen-10-yl]-5,7,8,10-tetrahydrodibenzo[f,h][1,4]dioxecine-7-carbaldehyde
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