(R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose

Modify Date: 2024-01-03 11:17:29

(R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose Structure
(R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose structure
Common Name (R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose
CAS Number 6612-91-5 Molecular Weight 294.30
Density 1.253 g/cm3 Boiling Point 432ºC at 760 mmHg
Molecular Formula C15H18O6 Melting Point N/A
MSDS N/A Flash Point 159.2ºC

 Use of (R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose


(R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name (6-hydroxy-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methyl benzoate
Synonym More Synonyms

  Biological Activity

Description (R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.253 g/cm3
Boiling Point 432ºC at 760 mmHg
Molecular Formula C15H18O6
Molecular Weight 294.30
Flash Point 159.2ºC
Exact Mass 294.11000
PSA 74.22000
LogP 1.08070

 Synthetic Route

 Synonyms

1,2-O-Isopropyliden-6-O-benzoyl-D-glucofuranose
5-O-CARBOMETHOXY-1,2-O-ISOPROPYLIDENE-D-XYLOFURANO
1,2-O-isopropylidene-5-O-methoxycarbonyl-D-xylofuranose
5-O-carbomethoxy-1,2-O-isopropylidene-*D-xylofura
5-O-Benzoyl-1,2-O-isopropyliden-D-ribofuranose
5-O-Carbomethoxy-1,2-O-isopropylidene-a-D-xylofuranose