2,3'-Bi-1H-indole,2,3-dihydro-

Modify Date: 2024-01-10 09:48:35

2,3'-Bi-1H-indole,2,3-dihydro- Structure
2,3'-Bi-1H-indole,2,3-dihydro- structure
Common Name 2,3'-Bi-1H-indole,2,3-dihydro-
CAS Number 6637-10-1 Molecular Weight 234.30
Density 1.225g/cm3 Boiling Point 449.3ºC at 760 mmHg
Molecular Formula C16H14N2 Melting Point N/A
MSDS N/A Flash Point 225.5ºC

 Use of 2,3'-Bi-1H-indole,2,3-dihydro-


VPC13163 is a potent androgen receptor (AR) BF3 inhibitor with an IC50 of 0.31 µM. VPC13163 has anticancer effects[1].

 Names

Name 3-[(2R)-2,3-dihydro-1H-indol-2-yl]-1H-indole
Synonym More Synonyms

 2,3'-Bi-1H-indole,2,3-dihydro- Biological Activity

Description VPC13163 is a potent androgen receptor (AR) BF3 inhibitor with an IC50 of 0.31 µM. VPC13163 has anticancer effects[1].
Related Catalog
Target

IC50: 0.31 µM (AR BF3)[1]

References

[1]. Ravi Shashi Nayana Munuganti, et al. Abstract 2508: The development of anti-androgens with a novel mechanism of action for treatment of castration-resistant prostate cancer. Cancer Res (2014) 74 (19_Supplement): 2508.

 Chemical & Physical Properties

Density 1.225g/cm3
Boiling Point 449.3ºC at 760 mmHg
Molecular Formula C16H14N2
Molecular Weight 234.30
Flash Point 225.5ºC
Exact Mass 234.11600
PSA 27.82000
LogP 4.01520
Index of Refraction 1.699

 Synthetic Route

 Synonyms

2,3-dihydro-1H,1'H-[2,3']biindolyl
3-(indolin-2-yl)indole
2,3-dihydro-(1,4)dioxino(2,3-c)pyridin-7-carbaldehyde
2-(3-indolyl)-2,3-dihydroindole
2H,3H-[1,4]dioxino[2,3-c]pyridine-7-carbaldehyde
2,3-Dihydro-<2,3'-biindole>
3-(indolin-2-yl)-1H-indole
2-(3'-indolyl)indoline
2-(indol-3-yl)-2,3-dihydroindole
2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxaldehyde
2,3-dihydro[1,4]dioxino[2,3-c]pyridine-7-carbaldehyde