1-(3-beta-Azido-2,3-dideoxy-5-O-trityl-beta-D-threopenta-furanosyl)thyMine

Modify Date: 2024-02-11 13:51:03

1-(3-beta-Azido-2,3-dideoxy-5-O-trityl-beta-D-threopenta-furanosyl)thyMine Structure
1-(3-beta-Azido-2,3-dideoxy-5-O-trityl-beta-D-threopenta-furanosyl)thyMine structure
Common Name 1-(3-beta-Azido-2,3-dideoxy-5-O-trityl-beta-D-threopenta-furanosyl)thyMine
CAS Number 66503-47-7 Molecular Weight 509.56
Density N/A Boiling Point N/A
Molecular Formula C29H27N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1-(3-beta-Azido-2,3-dideoxy-5-O-trityl-beta-D-threopenta-furanosyl)thyMine


1-(3-β-Azido-2,3-dideoxy-5-O-trityl-D-threopenta-furanosyl)thymine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-[3'-azido-2',3'-dideoxy-5'-(triphenylmethyl)-β-D-threo-pentofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione
Synonym More Synonyms

  Biological Activity

Description 1-(3-β-Azido-2,3-dideoxy-5-O-trityl-D-threopenta-furanosyl)thymine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C29H27N5O4
Molecular Weight 509.56
Exact Mass 509.20600
PSA 123.07000
LogP 4.27286

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

1-(3-Azido-2,3-dideoxy-5-O-trityl-β-D-threo-pentofuranosyl)thymine
1-(3'-azido-2',3'-dideoxy-5'-O-trityl-β-D-xylofuranosyl)thymine
1-(3-azido-O5-trityl-β-D-threo-2,3-dideoxy-pentofuranosyl)-5-methyl-1H-pyrimidine-2,4-dione