1-(4'-thio-beta-ribofuranosyl)thymine

Modify Date: 2024-02-28 17:06:21

1-(4'-thio-beta-ribofuranosyl)thymine Structure
1-(4'-thio-beta-ribofuranosyl)thymine structure
Common Name 1-(4'-thio-beta-ribofuranosyl)thymine
CAS Number 6741-71-5 Molecular Weight 274.29
Density N/A Boiling Point N/A
Molecular Formula C10H14N2O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1-(4'-thio-beta-ribofuranosyl)thymine


N6-Methyl-2-methyl thioadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-5-methylpyrimidine-2,4-dione
Synonym More Synonyms

 1-(4'-thio-beta-ribofuranosyl)thymine Biological Activity

Description N6-Methyl-2-methyl thioadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C10H14N2O5S
Molecular Weight 274.29
Exact Mass 274.06200
PSA 141.11000

 Synonyms

1-Ribo-4'-thiothymine
Uridine,5-methyl-4'-thio
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