BAY-678 racemate

Modify Date: 2024-01-08 20:45:54

BAY-678 racemate Structure
BAY-678 racemate structure
Common Name BAY-678 racemate
CAS Number 675103-35-2 Molecular Weight 400.35
Density N/A Boiling Point N/A
Molecular Formula C20H15F3N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BAY-678 racemate


BAY-678 racemate is a racemate of BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).

 Names

Name BAY-678 racemate

 BAY-678 racemate Biological Activity

Description BAY-678 racemate is a racemate of BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).
Related Catalog
References

[1]. von Nussbaum F, et al. Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases. ChemMedChem. 2015 Jul;10(7):1163-73.

 Chemical & Physical Properties

Molecular Formula C20H15F3N4O2
Molecular Weight 400.35
Storage condition 2-8℃
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Price: ¥1100/5 mg

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