Fenpropimorph

Modify Date: 2024-01-05 17:50:27

Fenpropimorph structure	Common Name	Fenpropimorph
	CAS Number	67564-91-4	Molecular Weight	303.48
	Density	0.928 g/cm3	Boiling Point	392.7ºC at 760 mmHg
	Molecular Formula	C₂₀H₃₃NO	Melting Point	25°C
	MSDS	Chinese USA	Flash Point	115.6ºC
	Symbol	GHS07, GHS08, GHS09	Signal Word	Warning

Use of Fenpropimorph

Fenpropimorph is a fungicide that inhibits the sterol pathway. Fenpropimorph inhibits δ8-δ7-sterol isomerase in yeast at low concentrations, with δ14-sterol reductase being blocked at higher levels, preventing the biosynthesis of ergosterol. Fenpropimorph also inhibits sterol synthesis in certain plants and mammalian cells[1][2][3].

Name	fenpropimorph
Synonym	More Synonyms

Description	Fenpropimorph is a fungicide that inhibits the sterol pathway. Fenpropimorph inhibits δ8-δ7-sterol isomerase in yeast at low concentrations, with δ14-sterol reductase being blocked at higher levels, preventing the biosynthesis of ergosterol. Fenpropimorph also inhibits sterol synthesis in certain plants and mammalian cells[1][2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Costet MF, et al. Ecdysteroid biosynthesis and embryonic development are disturbed in insects (Locusta migratoria) reared on plant diet (Triticum sativum) with a selectively modified sterol profile. Proc Natl Acad Sci U S A. 1987;84(3):643-647. [2]. Marcireau C, et al. In vivo effects of fenpropimorph on the yeast Saccharomyces cerevisiae and determination of the molecular basis of the antifungal property. Antimicrob Agents Chemother. 1990;34(6):989-993. [3]. Corio-Costet MF, et al. Inhibition by the fungicide fenpropimorph of cholesterol biosynthesis in 3T3 fibroblasts. Biochem J. 1988;256(3):829-834.

Description

Related Catalog

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

References

[1]. Costet MF, et al. Ecdysteroid biosynthesis and embryonic development are disturbed in insects (Locusta migratoria) reared on plant diet (Triticum sativum) with a selectively modified sterol profile. Proc Natl Acad Sci U S A. 1987;84(3):643-647.

[2]. Marcireau C, et al. In vivo effects of fenpropimorph on the yeast Saccharomyces cerevisiae and determination of the molecular basis of the antifungal property. Antimicrob Agents Chemother. 1990;34(6):989-993.

[3]. Corio-Costet MF, et al. Inhibition by the fungicide fenpropimorph of cholesterol biosynthesis in 3T3 fibroblasts. Biochem J. 1988;256(3):829-834.

Density	0.928 g/cm3
Boiling Point	392.7ºC at 760 mmHg
Melting Point	25°C
Molecular Formula	C₂₀H₃₃NO
Molecular Weight	303.48
Flash Point	115.6ºC
Exact Mass	303.25600
PSA	12.47000
LogP	4.20980
Index of Refraction	1.49

Fenpropimorph MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QE1940000

CHEMICAL NAME :: Morpholine, 2,6-dimethyl-4-(3-(4-(1,1-dimethylethyl)phenyl)-2-met hylpropyl)-, cis-

CAS REGISTRY NUMBER :: 67564-91-4

LAST UPDATED :: 199706

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C20-H33-N-O

MOLECULAR WEIGHT :: 303.54

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,379,1991

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2900 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,379,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,379,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5980 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,379,1991

Symbol	GHS07, GHS08, GHS09
Signal Word	Warning
Hazard Statements	H302-H315-H361d-H411
Precautionary Statements	P273-P281
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn: Harmful;N: Dangerous for the environment;
Risk Phrases	R22;R38;R51/53;R63
Safety Phrases	36/37-46-61
RIDADR	UN 3082
RTECS	QE1940000

2-CHLORO-2-METH...

CAS#:594-36-5

~0%

Amorolfine

CAS#:78613-35-1

Fenpropimorph

CAS#:67564-91-4

Literature: GALDERMA S.A. Patent: WO2007/12983 A2, 2007 ; Location in patent: Page/Page column 13-16 ;

bepromoline hyd...

CAS#:922734-43-8

2-CHLORO-2-METH...

CAS#:594-36-5

Amorolfine

CAS#:78613-35-1

Fenpropimorph

CAS#:67564-91-4

Literature: EP1935889 A1, ; Page/Page column 8-9 ;

Precursor 2
CAS#:594-36-5 2-CHLORO-2-METH... CAS#:922734-43-8 bepromoline hyd...
DownStream 0

cis-4-<3-(4-tert-butylphenyl)-2-methylpropyl>-2,6-dimethylmorpholine

4,10-dioxatricyclo[5.2.1.0<2,6>]decan-3,5-dione

Wln: T C555 A ao dvovtj

demethylcantharidin

(2R,6S)-rel-4-[3-[4-(1,1-dimethylethyl)phenyl]-2-methylpropyl]-2,6-dimethylmorpholine

rac-(2R,6S)-4-[(2Ξ)-3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine

3,6-Endooxyphthalic anhydride,hexahydro

MFCD00144306

rel-(2R,6S)-4-[3-[4-(1,1-dimethylethyl)phenyl]-2-methylpropyl]-2,6-dimethylmorpholine

hexahydro-4,7-epoxyisobenzofuran-1,3-dione

7-oxabicyclo[2,2,1]heptane-2,3-dicarboxylic acid anhydride

cis-exo-hexahydro-4,7-epoxyisobenzofuran-1,3-dione

4-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-2,6-dimethyl-morpholine

EINECS 266-719-9

Fenpropimorph

Demehylcantharidin

cis-4-[(RS)-3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine

Hexahydro-3,6-epoxyphthalic anhydride

Nocantharidin

cis-4-[3-(p-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine

(exo)hexahydro-4,7-epoxyisobenzofuran-1,3-dione

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Fenpropimorph
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Fenpropimorph
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Fenpropimorph
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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Fenpropimorph

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