BMS 193885

Modify Date: 2024-01-09 18:16:02

BMS 193885 Structure
BMS 193885 structure
Common Name BMS 193885
CAS Number 679839-66-8 Molecular Weight 680.79
Density N/A Boiling Point N/A
Molecular Formula C36H48N4O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BMS 193885


BMS-193885 (L-Lactic acid) is a potent, selective, and brain-penetrant neuropeptide Y1 receptor antagonist. BMS-193885 has a Ki value of 3.3 nM for the neuropeptide Y1 receptor, competitively acts on the neuropeptide Y binding site, and can reduce food intake and body weight through central Y1 inhibition[1].

 Names

Name BMS 193885
Synonym More Synonyms

 BMS 193885 Biological Activity

Description BMS-193885 (L-Lactic acid) is a potent, selective, and brain-penetrant neuropeptide Y1 receptor antagonist. BMS-193885 has a Ki value of 3.3 nM for the neuropeptide Y1 receptor, competitively acts on the neuropeptide Y binding site, and can reduce food intake and body weight through central Y1 inhibition[1].
Related Catalog
References

[1]. Ildiko Antal-Zimanyi, et al. Pharmacological characterization and appetite suppressive properties of BMS-193885, a novel and selective neuropeptide Y(1) receptor antagonist. Eur J Pharmacol. 2008 Aug 20;590(1-3):224-32.  

 Chemical & Physical Properties

Molecular Formula C36H48N4O9
Molecular Weight 680.79
Exact Mass 680.342102

 Synonyms

(2S)-2-Hydroxypropanoic acid - dimethyl 4-{3-[({3-[4-(3-methoxyphenyl)piperidin-1-yl]propyl}carbamoyl)amino]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (1:1)
(2S)-2-Hydroxypropanoic acid - dimethyl 4-{3-[({3-[4-(3-methoxyphenyl)-1-piperidinyl]propyl}carbamoyl)amino]phenyl}-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate (1:1)
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-[3-[[[[3-[4-(3-methoxyphenyl)-1-piperidinyl]propyl]amino]carbonyl]amino]phenyl]-2,6-dimethyl-, dimethyl ester, compd. with (2S)-2-hydroxypropanoic acid (1:1)