PDM 2
Modify Date: 2024-01-16 10:48:06
PDM 2 structure
|
Common Name | PDM 2 | ||
|---|---|---|---|---|
| CAS Number | 688348-25-6 | Molecular Weight | 283.580 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 394.2±42.0 °C at 760 mmHg | |
| Molecular Formula | C14H9Cl3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 276.5±23.5 °C | |
Use of PDM 2PDM2 is a selective, high-affinity aryl hydrocarbon receptor (AhR) antagonist with an Ki of 1.2±0.4 nM. |
| Name | 1,3-dichloro-5-[2-(4-chlorophenyl)ethenyl]benzene |
|---|---|
| Synonym | More Synonyms |
| Description | PDM2 is a selective, high-affinity aryl hydrocarbon receptor (AhR) antagonist with an Ki of 1.2±0.4 nM. |
|---|---|
| Related Catalog | |
| Target |
Ki: 1.2±0.4 nM(AhR)[1] |
| In Vitro | PDM2 (Compound 4b) exhibits a Ki of 1.2±0.4 nM for AhR and no affinity for estrogen receptor (ER), confirming that replacement of hydroxyl with chloride abolished binding on ER and increased dramatically the affinity for AhR[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 394.2±42.0 °C at 760 mmHg |
| Molecular Formula | C14H9Cl3 |
| Molecular Weight | 283.580 |
| Flash Point | 276.5±23.5 °C |
| Exact Mass | 281.976990 |
| LogP | 6.58 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.675 |
| Storage condition | 2-8℃ |
| 1,3-Dichloro-5-[(E)-2-(4-chlorophenyl)vinyl]benzene |
| 1,3-dichloro-5-[(E)-2-(4-chlorophenyl)ethenyl]benzene |
| Benzene, 1,3-dichloro-5-[(E)-2-(4-chlorophenyl)ethenyl]- |
| PDM 2 |