Name | 1,3-dichloro-5-[2-(4-chlorophenyl)ethenyl]benzene |
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Synonyms |
1,3-Dichloro-5-[(E)-2-(4-chlorophenyl)vinyl]benzene
1,3-dichloro-5-[(E)-2-(4-chlorophenyl)ethenyl]benzene Benzene, 1,3-dichloro-5-[(E)-2-(4-chlorophenyl)ethenyl]- PDM 2 |
Description | PDM2 is a selective, high-affinity aryl hydrocarbon receptor (AhR) antagonist with an Ki of 1.2±0.4 nM. |
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Related Catalog | |
Target |
Ki: 1.2±0.4 nM(AhR)[1] |
In Vitro | PDM2 (Compound 4b) exhibits a Ki of 1.2±0.4 nM for AhR and no affinity for estrogen receptor (ER), confirming that replacement of hydroxyl with chloride abolished binding on ER and increased dramatically the affinity for AhR[1]. |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 394.2±42.0 °C at 760 mmHg |
Molecular Formula | C14H9Cl3 |
Molecular Weight | 283.580 |
Flash Point | 276.5±23.5 °C |
Exact Mass | 281.976990 |
LogP | 6.58 |
Vapour Pressure | 0.0±0.9 mmHg at 25°C |
Index of Refraction | 1.675 |
Storage condition | 2-8℃ |