Luteolin-4'-O-glucoside

Modify Date: 2024-01-02 23:48:38

Luteolin-4'-O-glucoside Structure
Luteolin-4'-O-glucoside structure
 Common Name Luteolin-4'-O-glucoside
CAS Number 6920-38-3 Molecular Weight 448.37700
Density 1.713g/cm3 Boiling Point 814.5ºC at 760 mmHg
Molecular Formula C21H20O11 Melting Point 210ºC (dec.)
MSDS N/A Flash Point 288.5ºC

 Use of Luteolin-4'-O-glucoside


Luteolin-4'-O-glucoside is an IL-5 inhibitor with an IC50 of 3.7 μM. Luteolin-4'-O-glucoside resists hyperuricemia and acute gouty arthritis activity. Luteolin-4'-O-glucoside shows anticancer activity[1][2][3].

 Names

Name luteolin-4'-o-glucoside
Synonym More Synonyms

 Luteolin-4'-O-glucoside Biological Activity

Description Luteolin-4'-O-glucoside is an IL-5 inhibitor with an IC50 of 3.7 μM. Luteolin-4'-O-glucoside resists hyperuricemia and acute gouty arthritis activity. Luteolin-4'-O-glucoside shows anticancer activity[1][2][3].
Related Catalog
Target

IC50: 3.7 μM (IL-5)[1]

In Vitro Luteolin-4'-O-glucoside shows cytotoxic activity against NCI-H929, U266, and OPM2 cell lines[3].
References

[1]. Park KY, et al. Inhibitory effect of luteolin 4'-O-glucoside from Kummerowia striata and other flavonoids on interleukin-5 bioactivity. Planta Med. 1999 Jun;65(5):457-9.

[2]. Lin Y, et al. Luteolin-4'-O-glucoside and its aglycone, two major flavones of Gnaphalium affine D. Don, resist hyperuricemia and acute gouty arthritis activity in animal models. Phytomedicine. 2018 Mar 1;41:54-61.

[3]. Xu T, et al. Glycosylation of luteolin in hydrophilic organic solvents and structure–antioxidant relationships of luteolin glycosides. RSC Advances, 2022, 12(28): 18232-18237.

 Chemical & Physical Properties

Density 1.713g/cm3
Boiling Point 814.5ºC at 760 mmHg
Melting Point 210ºC (dec.)
Molecular Formula C21H20O11
Molecular Weight 448.37700
Flash Point 288.5ºC
Exact Mass 448.10100
PSA 190.28000
Index of Refraction 1.74

 Safety Information

Hazard Codes Xi

 Synonyms

luteolin-4'-glucoside
3',4',5,7-tetrahydroxyflavone-4'-glucoside
MFCD00017468
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