Atractylon

Modify Date: 2024-01-03 06:39:48

Atractylon Structure
Atractylon structure
Common Name Atractylon
CAS Number 6989-21-5 Molecular Weight 216.319
Density 1.0±0.1 g/cm3 Boiling Point 287.1±19.0 °C at 760 mmHg
Molecular Formula C15H20O Melting Point 61-63℃
MSDS N/A Flash Point 121.7±8.3 °C

 Use of Atractylon


Atractylone (Atractylon) is a sesquiterpenoid extracted from Atractylodis Rhizoma. Atractylone (Atractylon) alleviates influenza A virus (IAV)-induced lung injury via regulating the TLR7 signaling pathway, and acts as a promising agent for IAV treatment. Atractylone (Atractylon) inhibits the degranulation of mast cell and exhibits potential for the treatment of mast cell-mediated allergic reactions[1][2].

 Names

Name (4aS,8aR)-3,8a-Dimethyl-5-methylene-4,4a,5,6,7,8,8a,9-octahydronaphtho[2,3-b]furan
Synonym More Synonyms

 Atractylon Biological Activity

Description Atractylone (Atractylon) is a sesquiterpenoid extracted from Atractylodis Rhizoma. Atractylone (Atractylon) alleviates influenza A virus (IAV)-induced lung injury via regulating the TLR7 signaling pathway, and acts as a promising agent for IAV treatment. Atractylone (Atractylon) inhibits the degranulation of mast cell and exhibits potential for the treatment of mast cell-mediated allergic reactions[1][2].
Related Catalog
References

[1]. Cheng Y, et al. Antiviral activities of atractylon from Atractylodis Rhizoma. Mol Med Rep. 2016 Oct;14(4):3704-10.

[2]. Han NR, et al. Inhibitory effects of atractylone on mast cell-mediated allergic reactions. Chem Biol Interact. 2016 Oct 25;258:59-68.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 287.1±19.0 °C at 760 mmHg
Melting Point 61-63℃
Molecular Formula C15H20O
Molecular Weight 216.319
Flash Point 121.7±8.3 °C
Exact Mass 216.151413
PSA 13.14000
LogP 5.57
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.535
Storage condition 2-8C

 Synonyms

Naphtho[2,3-b]furan, 4,4a,5,6,7,8,8a,9-octahydro-3,8a-dimethyl-5-methylene-, (4aS,8aR)-
(4aS,8aR)-3,8a-dimethyl-5-methylidene-4,4a,6,7,8,9-hexahydrobenzo[f][1]benzofuran
(4aS,8aR)-3,8a-Dimethyl-5-methylene-4,4a,5,6,7,8,8a,9-octahydronaphtho[2,3-b]furan
Atractylon
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