Obtusin

Modify Date: 2024-01-02 22:56:52

Obtusin Structure
Obtusin structure
Common Name Obtusin
CAS Number 70588-05-5 Molecular Weight 344.315
Density 1.4±0.1 g/cm3 Boiling Point 614.9±55.0 °C at 760 mmHg
Molecular Formula C18H16O7 Melting Point N/A
MSDS N/A Flash Point 227.0±25.0 °C

 Use of Obtusin


Obtusin, isolated from Cassia obtusifolia Linn seed, is a highly selective and competitive human monoamine oxidase-A (hMAO-A) inhibitor with an IC50 of 11.12 μM and a Ki of 6.15. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression[1].

 Names

Name Obtusin
Synonym More Synonyms

 Obtusin Biological Activity

Description Obtusin, isolated from Cassia obtusifolia Linn seed, is a highly selective and competitive human monoamine oxidase-A (hMAO-A) inhibitor with an IC50 of 11.12 μM and a Ki of 6.15. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression[1].
Related Catalog
Target

IC50: 11.12 μM (hMAO-A)[1] Ki: 6.15 (hMAO-A)[1]

References

[1]. Paudel P, et al. In Vitro and in Silico Human Monoamine Oxidase Inhibitory Potential of Anthraquinones, Naphthopyrones, and Naphthalenic Lactones from Cassia obtusifolia Linn Seeds. ACS Omega. 2019 Sep 18;4(14):16139-16152.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 614.9±55.0 °C at 760 mmHg
Molecular Formula C18H16O7
Molecular Weight 344.315
Flash Point 227.0±25.0 °C
Exact Mass 344.089600
PSA 102.29000
LogP 4.10
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.634
Storage condition 2-8℃

 Safety Information

HS Code 2914690090

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2914690090
Summary 2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Synonyms

9,10-Anthracenedione, 1,7-dihydroxy-2,3,8-trimethoxy-6-methyl-
1,7-dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione
1,7-Dihydroxy-2,3,8-trimethoxy-6-methyl-9,10-anthraquinone
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